CRCGN016_MCF10A.WT.HP_24H:F06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description triclosan 11.22 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

27 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:F06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AMDHD2 amidohydrolase domain containing 2 4.42536
SSBP2 single-stranded DNA binding protein 2 3.29532
DHRS2 dehydrogenase/reductase (SDR family) member 2 3.21708
OLFML2B olfactomedin-like 2B 2.85396
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.59605
KIF5C kinesin family member 5C 2.56014
PNKP polynucleotide kinase 3'-phosphatase 2.55673
RPP38 ribonuclease P/MRP 38kDa subunit 2.41256
ABHD6 abhydrolase domain containing 6 2.37667
CDC45 cell division cycle 45 2.28192

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -4.45037
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.58335
TES testin LIM domain protein -3.51526
CIAPIN1 cytokine induced apoptosis inhibitor 1 -3.44604
CAB39 calcium binding protein 39 -3.26383
BASP1 brain abundant, membrane attached signal protein 1 -3.2104
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -3.12964
SGK1 serum/glucocorticoid regulated kinase 1 -3.07257
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.03482
GDF15 growth differentiation factor 15 -2.89757
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -2.89607
KRT14 keratin 14, type I -2.76047
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.67458
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.31681
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.27773
TMEM242 transmembrane protein 242 -2.02543
INSIG1 insulin induced gene 1 -2.02275