CRCGN016_MCF10A.WT.HP_24H:F07 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description nitrosoethylmethylamine 99.45 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:F07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 5.67406
ACAA1 acetyl-CoA acyltransferase 1 2.95232
AGR2 anterior gradient 2 2.85379
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.81689
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 2.80313
CXCR4 chemokine (C-X-C motif) receptor 4 2.74257
PLTP phospholipid transfer protein 2.70728
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.36983
RNF111 ring finger protein 111 2.3338
TRIM24 tripartite motif containing 24 2.2401
NUP205 nucleoporin 205kDa 2.17581
VWF von Willebrand factor 2.11796
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 2.04055

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -5.29839
HMG20B high mobility group 20B -5.02072
PUF60 poly-U binding splicing factor 60KDa -4.87604
CD44 CD44 molecule (Indian blood group) -4.2286
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -4.08226
TRAPPC3 trafficking protein particle complex 3 -3.43235
CLASRP CLK4-associating serine/arginine rich protein -2.28335
PDCD6 programmed cell death 6 -2.24146
MT1X metallothionein 1X -2.17536
SCRIB scribbled planar cell polarity protein -2.09737
CBR3 carbonyl reductase 3 -2.09212
POLG2 polymerase (DNA directed), gamma 2, accessory subunit -2.05413
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) -2.03097