CRCGN016_MCF10A.WT.HP_24H:F08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description nitrosoethylmethylamine 33.15 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

49 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:F08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGR2 anterior gradient 2 4.36553
EAPP E2F-associated phosphoprotein 3.64043
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 3.26963
GPER1 G protein-coupled estrogen receptor 1 3.13027
TBX2 T-box 2 2.89475
CXCR4 chemokine (C-X-C motif) receptor 4 2.86799
PDIA5 protein disulfide isomerase family A, member 5 2.65121
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 2.52036
RPH3AL rabphilin 3A-like (without C2 domains) 2.38588
SNRPD3 small nuclear ribonucleoprotein D3 polypeptide 18kDa 2.35272
BACE2 beta-site APP-cleaving enzyme 2 2.284
DDIT4 DNA-damage-inducible transcript 4 2.27875
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 2.19922
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 2.16219
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.13335
GSTM3 glutathione S-transferase mu 3 (brain) 2.12435
COL9A3 collagen, type IX, alpha 3 2.05643
OLFML2B olfactomedin-like 2B 2.04438
SRP54 signal recognition particle 54kDa 2.0412
RIOK2 RIO kinase 2 2.01965
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.01196

decreased expression

Symbol Name Standardized Value
GRB7 growth factor receptor-bound protein 7 -4.78866
GDF15 growth differentiation factor 15 -4.65058
SGK1 serum/glucocorticoid regulated kinase 1 -4.26282
MPC2 mitochondrial pyruvate carrier 2 -4.04601
HMG20B high mobility group 20B -3.77327
PGAP3 post-GPI attachment to proteins 3 -3.29961
KIF14 kinesin family member 14 -3.21814
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.05194
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.71839
MFSD12 major facilitator superfamily domain containing 12 -2.69483
LYPLA1 lysophospholipase I -2.62681
CD81 CD81 molecule -2.60429
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8 -2.51949
STARD3 StAR-related lipid transfer (START) domain containing 3 -2.44617
GSDMB gasdermin B -2.40274
UBE2W ubiquitin-conjugating enzyme E2W (putative) -2.32175
COPS7A COP9 signalosome subunit 7A -2.25597
CORO1A coronin, actin binding protein, 1A -2.20047
GLRX2 glutaredoxin 2 -2.19137
TRIM2 tripartite motif containing 2 -2.18442
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 -2.18411
SOX17 SRY (sex determining region Y)-box 17 -2.14954
ARL2BP ADP-ribosylation factor-like 2 binding protein -2.14206
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -2.08341
LYZL6 lysozyme-like 6 -2.07917
TENT4A terminal nucleotidyltransferase 4A -2.05021
SIRPA signal-regulatory protein alpha -2.0242
MTERF3 mitochondrial transcription termination factor 3 -2.01204