CRCGN016_MCF10A.WT.HP_24H:F09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description nitrosoethylmethylamine 11.05 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:F09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.8597
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 2.5066
DENND2D DENN/MADD domain containing 2D 2.44595
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 2.4214
ACAA1 acetyl-CoA acyltransferase 1 2.39873
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.28485
SLC75A1 solute carrier family 75 member 1 2.0773
MAPK9 mitogen-activated protein kinase 9 2.02077

decreased expression

Symbol Name Standardized Value
ADI1 acireductone dioxygenase 1 -5.33725
RNF167 ring finger protein 167 -4.83385
CCNB1 cyclin B1 -4.7964
ARID4B AT rich interactive domain 4B (RBP1-like) -4.7378
HSPA8 heat shock 70kDa protein 8 -4.718
LYPLA1 lysophospholipase I -3.58892
FOS FBJ murine osteosarcoma viral oncogene homolog -3.49655
BASP1 brain abundant, membrane attached signal protein 1 -3.46285
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -3.0685
MPC2 mitochondrial pyruvate carrier 2 -2.6736
CREG1 cellular repressor of E1A-stimulated genes 1 -2.631
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.18
LYPD3 LY6/PLAUR domain containing 3 -2.14355
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.1284
RAP2A RAP2A, member of RAS oncogene family -2.0977
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) -2.0803
RBM12B RNA binding motif protein 12B -2.0345
FOSB FBJ murine osteosarcoma viral oncogene homolog B -2.0156