CRCGN016_MCF10A.WT.HP_24H:F10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description eugenol 100.46 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

27 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:F10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
INTS3 integrator complex subunit 3 5.0465
KLHL21 kelch-like family member 21 4.70903
AGR2 anterior gradient 2 4.67458
SNAP25 synaptosomal-associated protein, 25kDa 4.61504
TCEA2 transcription elongation factor A (SII), 2 3.85184
ACAA1 acetyl-CoA acyltransferase 1 3.62966
HDGFL3 HDGF like 3 3.35349
MICALL1 MICAL-like 1 3.06185
SATB1 SATB homeobox 1 3.02917
ABHD4 abhydrolase domain containing 4 2.94379
RPP38 ribonuclease P/MRP 38kDa subunit 2.68644
VGLL4 vestigial-like family member 4 2.65297
COMP cartilage oligomeric matrix protein 2.54473
IGFBP3 insulin-like growth factor binding protein 3 2.28516
GET1 guided entry of tail-anchored proteins factor 1 2.19025

decreased expression

Symbol Name Standardized Value
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -5.25756
TES testin LIM domain protein -4.45236
ITFG1 integrin alpha FG-GAP repeat containing 1 -4.37437
GDF15 growth differentiation factor 15 -4.25178
SLC25A46 solute carrier family 25, member 46 -4.06016
XPO7 exportin 7 -3.63922
PMM2 phosphomannomutase 2 -2.56264
TENT4A terminal nucleotidyltransferase 4A -2.33432
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -2.27015
FAIM Fas apoptotic inhibitory molecule -2.20855
NISCH nischarin -2.10271
ZNF23 zinc finger protein 23 -2.06199