CRCGN016_MCF10A.WT.HP_24H:F11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description eugenol 33.49 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:F11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
COMP cartilage oligomeric matrix protein 4.41375
ACAA1 acetyl-CoA acyltransferase 1 3.94035
AGR2 anterior gradient 2 3.71517
SPAG4 sperm associated antigen 4 3.18246
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.93472
GET1 guided entry of tail-anchored proteins factor 1 2.847
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 2.6253
ANO10 anoctamin 10 2.60687
ACTA2 actin, alpha 2, smooth muscle, aorta 2.4599
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.36614
MYLK myosin light chain kinase 2.27342
E2F2 E2F transcription factor 2 2.13015
CIAO3 cytosolic iron-sulfur assembly component 3 2.1107
WIF1 WNT inhibitory factor 1 2.06855

decreased expression

Symbol Name Standardized Value
HMG20B high mobility group 20B -7.02205
BASP1 brain abundant, membrane attached signal protein 1 -2.9026
NT5DC2 5'-nucleotidase domain containing 2 -2.73296
TENT4A terminal nucleotidyltransferase 4A -2.63279
DSG2 desmoglein 2 -2.59392
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.55201
MFSD12 major facilitator superfamily domain containing 12 -2.43023
MT1X metallothionein 1X -2.41682
CBR3 carbonyl reductase 3 -2.19267
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma -2.16627
PMM2 phosphomannomutase 2 -2.11492