CRCGN016_MCF10A.WT.HP_24H:F14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description thiram 33.32 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

956 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:F14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CEMIP2 cell migration inducing hyaluronidase 2 10.0
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 10.0
WIF1 WNT inhibitory factor 1 9.9952
GADD45B growth arrest and DNA-damage-inducible, beta 9.88618
FOS FBJ murine osteosarcoma viral oncogene homolog 9.78164
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 8.81918
HSPA1A heat shock 70kDa protein 1A 8.57988
NUP93 nucleoporin 93kDa 7.96295
HMOX1 heme oxygenase 1 7.56259
TRIB1 tribbles pseudokinase 1 7.47787
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 7.09345
CXCL2 chemokine (C-X-C motif) ligand 2 6.83574
COMP cartilage oligomeric matrix protein 6.72558
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 6.59568
EGR1 early growth response 1 6.31173
AGR2 anterior gradient 2 6.15917
HSPA1B heat shock 70kDa protein 1B 6.07255
UGDH UDP-glucose 6-dehydrogenase 6.01661
CADM1 cell adhesion molecule 1 5.86209
GATA2 GATA binding protein 2 5.69656
TUBB6 tubulin, beta 6 class V 5.54538
ADRB2 adrenoceptor beta 2, surface 5.45034
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 5.35836
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 5.04429
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 4.99974
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 4.82504
IER2 immediate early response 2 4.64253
COL4A1 collagen, type IV, alpha 1 4.57908
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.56921
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 4.54918
IL1B interleukin 1, beta 4.54721
HSPA6 heat shock 70kDa protein 6 (HSP70B') 4.43894
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 4.39824
H2BC9 H2B clustered histone 9 4.32718
ABHD6 abhydrolase domain containing 6 4.26848
TGFB1I1 transforming growth factor beta 1 induced transcript 1 4.25493
FHL2 four and a half LIM domains 2 4.24936
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 4.21229
JMJD6 jumonji domain containing 6 4.15055
FOSB FBJ murine osteosarcoma viral oncogene homolog B 4.14262
CCL3L3 chemokine (C-C motif) ligand 3-like 3 4.13742
BZW2 basic leucine zipper and W2 domains 2 4.06935
BAG3 BCL2-associated athanogene 3 4.00683
IER5 immediate early response 5 3.99426
MMP1 matrix metallopeptidase 1 3.93393
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 3.92652
GADD45G growth arrest and DNA-damage-inducible, gamma 3.81257
PPY pancreatic polypeptide 3.78923
IBSP integrin-binding sialoprotein 3.77911
BAMBI BMP and activin membrane-bound inhibitor 3.7507
MARCO macrophage receptor with collagenous structure 3.74379
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 3.73193
TPM1 tropomyosin 1 (alpha) 3.72736
SLC35B1 solute carrier family 35, member B1 3.72439
DLX5 distal-less homeobox 5 3.69126
SART1 squamous cell carcinoma antigen recognized by T cells 3.63862
CD83 CD83 molecule 3.61886
CCL4 chemokine (C-C motif) ligand 4 3.6047
PPP1R15A protein phosphatase 1, regulatory subunit 15A 3.58484
MRPL18 mitochondrial ribosomal protein L18 3.5621
TPST2 tyrosylprotein sulfotransferase 2 3.56069
MSX2 msh homeobox 2 3.55154
MVP major vault protein 3.54331
LGMN legumain 3.54149
H2BC4 H2B clustered histone 4 3.54092
ALAS1 5'-aminolevulinate synthase 1 3.5386
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 3.46739
MYL9 myosin, light chain 9, regulatory 3.46053
PDE8B phosphodiesterase 8B 3.45859
ADRM1 adhesion regulating molecule 1 3.43677
AMIGO2 adhesion molecule with Ig-like domain 2 3.42847
JUN jun proto-oncogene 3.38529
VEGFC vascular endothelial growth factor C 3.36031
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 3.34375
PLEK2 pleckstrin 2 3.3388
CCDC92 coiled-coil domain containing 92 3.31462
NALF1 NALCN channel auxiliary factor 1 3.31085
LOC102724023 ES1 protein homolog, mitochondrial 3.25429
ECH1 enoyl CoA hydratase 1, peroxisomal 3.25011
ACTG2 actin, gamma 2, smooth muscle, enteric 3.24657
TBX3 T-box 3 3.24056
H2BC3 H2B clustered histone 3 3.23604
IGFBP3 insulin-like growth factor binding protein 3 3.22076
ALDOC aldolase C, fructose-bisphosphate 3.20131
DRAP1 DR1-associated protein 1 (negative cofactor 2 alpha) 3.14999
SH2D2A SH2 domain containing 2A 3.1325
AVEN apoptosis, caspase activation inhibitor 3.11296
SPHK1 sphingosine kinase 1 3.10457
INHBA inhibin, beta A 3.10243
TBPL1 TBP-like 1 3.09568
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 3.09111
FZD1 frizzled class receptor 1 3.05296
EDN1 endothelin 1 3.05228
RGS16 regulator of G-protein signaling 16 3.0475
ZC2HC1A zinc finger, C2HC-type containing 1A 3.04345
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 3.03618
FGFR4 fibroblast growth factor receptor 4 3.02054
HYI hydroxypyruvate isomerase (putative) 3.00552
H2AC7 H2A clustered histone 7 2.99632
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 2.9927
PDCL3 phosducin-like 3 2.98517
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 2.97836
BCOR BCL6 corepressor 2.97315
FAM50A family with sequence similarity 50, member A 2.96529
IFNG interferon, gamma 2.96292
CA6 carbonic anhydrase VI 2.95701
SMAD7 SMAD family member 7 2.94787
RAI14 retinoic acid induced 14 2.93717
GADD45A growth arrest and DNA-damage-inducible, alpha 2.93458
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) 2.93342
PDIA5 protein disulfide isomerase family A, member 5 2.92399
EGR4 early growth response 4 2.92216
C2CD2 C2 calcium-dependent domain containing 2 2.90199
ANXA8L1 annexin A8-like 1 2.89056
CXCL3 chemokine (C-X-C motif) ligand 3 2.87869
NGRN neugrin, neurite outgrowth associated 2.86749
PZP pregnancy-zone protein 2.86566
RMC1 regulator of MON1-CCZ1 2.86399
RAB21 RAB21, member RAS oncogene family 2.85731
H3-4 H3.4 histone, cluster member 2.85537
SMIM29 small integral membrane protein 29 2.853
HYOU1 hypoxia up-regulated 1 2.85223
CBR3 carbonyl reductase 3 2.84795
TMEM101 transmembrane protein 101 2.84638
H2AC4 H2A clustered histone 4 2.84125
TUFT1 tuftelin 1 2.84039
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 2.83413
NANS N-acetylneuraminic acid synthase 2.83412
PTPRC protein tyrosine phosphatase, receptor type, C 2.83358
MICB MHC class I polypeptide-related sequence B 2.83305
ZNF331 zinc finger protein 331 2.81953
THUMPD2 THUMP domain containing 2 2.80043
PLA2G15 phospholipase A2, group XV 2.79828
FGF5 fibroblast growth factor 5 2.79544
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 2.78688
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 2.78407
CDKN2AIP CDKN2A interacting protein 2.78357
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.78295
SH2B3 SH2B adaptor protein 3 2.78157
EBNA1BP2 EBNA1 binding protein 2 2.77812
FOXF2 forkhead box F2 2.77592
SHBG sex hormone-binding globulin 2.76752
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 2.76447
STIMATE STIM activating enhancer 2.76309
H3C7 H3 clustered histone 7 2.75982
SMAD9 SMAD family member 9 2.75317
PLCB4 phospholipase C, beta 4 2.7485
NACAD NAC alpha domain containing 2.74306
FRS2 fibroblast growth factor receptor substrate 2 2.72502
DOK2 docking protein 2, 56kDa 2.71337
STIP1 stress-induced phosphoprotein 1 2.71193
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 2.71173
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 2.70613
FNBP1L formin binding protein 1-like 2.70438
LOC102724428 serine/threonine-protein kinase SIK1 2.70074
AMBN ameloblastin (enamel matrix protein) 2.70064
TCP11L1 t-complex 11, testis-specific-like 1 2.69712
RGS2 regulator of G-protein signaling 2 2.69337
CORO1A coronin, actin binding protein, 1A 2.69318
PERP PERP, TP53 apoptosis effector 2.68729
GJA1 gap junction protein, alpha 1, 43kDa 2.68589
H2BC14 H2B clustered histone 14 2.68371
H2BC12 H2B clustered histone 12 2.66443
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 2.66104
SKIL SKI-like proto-oncogene 2.6577
HBEGF heparin-binding EGF-like growth factor 2.65433
H3-3B H3.3 histone B 2.64741
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 2.6323
VAMP8 vesicle-associated membrane protein 8 2.60996
ACTC1 actin, alpha, cardiac muscle 1 2.59834
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.59646
KLF10 Kruppel-like factor 10 2.59552
GBX2 gastrulation brain homeobox 2 2.58942
CNN1 calponin 1, basic, smooth muscle 2.58918
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 2.58615
TEX14 testis expressed 14 2.56396
SLC10A3 solute carrier family 10, member 3 2.54822
DCTN1 dynactin 1 2.54141
HOXB13 homeobox B13 2.53556
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 2.53546
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1 2.53531
PTPN21 protein tyrosine phosphatase, non-receptor type 21 2.53127
EOLA1 endothelium and lymphocyte associated ASCH domain 1 2.52346
FOXL2 forkhead box L2 2.52304
PTPRK protein tyrosine phosphatase, receptor type, K 2.52077
AFF4 AF4/FMR2 family, member 4 2.52036
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 2.51463
THSD1 thrombospondin, type I, domain containing 1 2.51297
THSD7A thrombospondin, type I, domain containing 7A 2.50885
CAB39L calcium binding protein 39-like 2.50517
SCCPDH saccharopine dehydrogenase (putative) 2.5011
FGF3 fibroblast growth factor 3 2.49928
SNAI1 snail family zinc finger 1 2.49535
PAPSS1 3'-phosphoadenosine 5'-phosphosulfate synthase 1 2.49529
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 2.49233
NUAK1 NUAK family, SNF1-like kinase, 1 2.49015
CTLA4 cytotoxic T-lymphocyte-associated protein 4 2.48782
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 2.486
CCDC86 coiled-coil domain containing 86 2.48037
THBD thrombomodulin 2.47318
CALML5 calmodulin-like 5 2.47232
SEC61B Sec61 beta subunit 2.47124
ALOXE3 arachidonate lipoxygenase 3 2.47005
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 2.46474
TCP1 t-complex 1 2.46088
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 2.45963
SDF2L1 stromal cell-derived factor 2-like 1 2.45087
COL9A3 collagen, type IX, alpha 3 2.44962
NAGK N-acetylglucosamine kinase 2.44569
LRRC59 leucine rich repeat containing 59 2.44429
GNL2 guanine nucleotide binding protein-like 2 (nucleolar) 2.4433
RNASEH2A ribonuclease H2, subunit A 2.4408
DLX2 distal-less homeobox 2 2.44043
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 2.4371
SMR3A submaxillary gland androgen regulated protein 3A 2.43525
SNAI2 snail family zinc finger 2 2.43458
NUP58 nucleoporin 58 2.43408
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 2.43337
PTK7 protein tyrosine kinase 7 (inactive) 2.42742
RAB3B RAB3B, member RAS oncogene family 2.42467
INA internexin neuronal intermediate filament protein, alpha 2.42232
RAP1A RAP1A, member of RAS oncogene family 2.41354
LOC102724594 splicing factor U2AF 35 kDa subunit 2.41088
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 2.4082
CYTIP cytohesin 1 interacting protein 2.40651
HSPH1 heat shock 105kDa/110kDa protein 1 2.40323
RASL10A RAS-like, family 10, member A 2.40169
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19 2.39915
SSTR1 somatostatin receptor 1 2.39398
EN2 engrailed homeobox 2 2.39124
DNASE2B deoxyribonuclease II beta 2.38941
CTSZ cathepsin Z 2.3864
KRT34 keratin 34, type I 2.38637
PTPN1 protein tyrosine phosphatase, non-receptor type 1 2.38377
ZNF34 zinc finger protein 34 2.38369
MYH9 myosin, heavy chain 9, non-muscle 2.37619
GHRH growth hormone releasing hormone 2.3735
LAP3 leucine aminopeptidase 3 2.36914
ILKAP integrin-linked kinase-associated serine/threonine phosphatase 2.366
LPO lactoperoxidase 2.36479
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2 2.35854
SMIM40 small integral membrane protein 40 2.35367
DLL3 delta-like 3 (Drosophila) 2.35071
TMEM143 transmembrane protein 143 2.3495
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 2.34559
GBP2 guanylate binding protein 2, interferon-inducible 2.34078
DOT1L DOT1-like histone H3K79 methyltransferase 2.3367
YEATS2 YEATS domain containing 2 2.32966
RBM6 RNA binding motif protein 6 2.32377
CRISP3 cysteine-rich secretory protein 3 2.3232
PTHLH parathyroid hormone-like hormone 2.32156
TMEM132A transmembrane protein 132A 2.31882
CD69 CD69 molecule 2.31527
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 2.31516
TSHR thyroid stimulating hormone receptor 2.3129
GGTLC1 gamma-glutamyltransferase light chain 1 2.30572
VSIG4 V-set and immunoglobulin domain containing 4 2.30062
SYNC syncoilin, intermediate filament protein 2.29964
BRMS1L breast cancer metastasis-suppressor 1-like 2.29858
RNASE7 ribonuclease, RNase A family, 7 2.29674
KRTAP1-3 keratin associated protein 1-3 2.29653
PAX7 paired box 7 2.29383
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 2.29048
HBZ hemoglobin, zeta 2.28938
WDR4 WD repeat domain 4 2.28789
RNFT1 ring finger protein, transmembrane 1 2.28403
DLX6 distal-less homeobox 6 2.28366
CTSL cathepsin L 2.28266
ZBED2 zinc finger, BED-type containing 2 2.27995
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 2.27973
SLC31A2 solute carrier family 31 (copper transporter), member 2 2.27847
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 2.27596
PHLDA2 pleckstrin homology-like domain, family A, member 2 2.27109
EN1 engrailed homeobox 1 2.26787
SAP30BP SAP30 binding protein 2.26691
MN1 meningioma (disrupted in balanced translocation) 1 2.26684
LAGE3 L antigen family, member 3 2.26635
GLT8D2 glycosyltransferase 8 domain containing 2 2.26613
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1 2.26521
POGLUT2 protein O-glucosyltransferase 2 2.2637
RNF113A ring finger protein 113A 2.26186
THBS1 thrombospondin 1 2.26179
DNASE1L1 deoxyribonuclease I-like 1 2.2585
HPGDS hematopoietic prostaglandin D synthase 2.25798
IL10RA interleukin 10 receptor, alpha 2.25679
ADAM11 ADAM metallopeptidase domain 11 2.25618
H1-5 H1.5 linker histone, cluster member 2.24638
POPDC2 popeye domain containing 2 2.24445
H2BC5 H2B clustered histone 5 2.24421
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 2.23611
GPRASP1 G protein-coupled receptor associated sorting protein 1 2.23416
CCNE2 cyclin E2 2.23376
BARX1 BARX homeobox 1 2.23321
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) 2.23293
CNTN1 contactin 1 2.23246
FCN3 ficolin (collagen/fibrinogen domain containing) 3 2.23173
H1-3 H1.3 linker histone, cluster member 2.23123
FXYD6-FXYD2 FXYD6-FXYD2 readthrough 2.22871
IL22 interleukin 22 2.22864
GNA14 guanine nucleotide binding protein (G protein), alpha 14 2.22705
ZNF532 zinc finger protein 532 2.22603
ZNF682 zinc finger protein 682 2.22566
KRT83 keratin 83, type II 2.22015
SH2D3C SH2 domain containing 3C 2.21959
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 2.21739
LSR lipolysis stimulated lipoprotein receptor 2.2149
ADM adrenomedullin 2.2143
AKT1 v-akt murine thymoma viral oncogene homolog 1 2.21355
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 2.21193
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 2.21044
DPP3 dipeptidyl-peptidase 3 2.20797
GPRC5D G protein-coupled receptor, class C, group 5, member D 2.20742
PLAU plasminogen activator, urokinase 2.20663
LBP lipopolysaccharide binding protein 2.20567
PDE10A phosphodiesterase 10A 2.20421
NUDC nudC nuclear distribution protein 2.20372
ANKRD44 ankyrin repeat domain 44 2.20147
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase 2.20006
MYO19 myosin XIX 2.19909
PLEKHA5 pleckstrin homology domain containing, family A member 5 2.19533
MEX3D mex-3 RNA binding family member D 2.19406
IRS1 insulin receptor substrate 1 2.19252
CRX cone-rod homeobox 2.19201
HHEX hematopoietically expressed homeobox 2.19162
RAB15 RAB15, member RAS oncogene family 2.19009
NKX3-2 NK3 homeobox 2 2.18996
DUSP28 dual specificity phosphatase 28 2.18891
DUSP12 dual specificity phosphatase 12 2.18844
C3AR1 complement component 3a receptor 1 2.18172
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 2.18051
CLEC5A C-type lectin domain family 5, member A 2.18045
SMCO4 single-pass membrane protein with coiled-coil domains 4 2.1802
CRABP1 cellular retinoic acid binding protein 1 2.17981
XCL1 chemokine (C motif) ligand 1 2.17637
LALBA lactalbumin, alpha- 2.17173
CDK2AP2 cyclin-dependent kinase 2 associated protein 2 2.17153
DUSP7 dual specificity phosphatase 7 2.16407
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 2.16267
HABP2 hyaluronan binding protein 2 2.1615
SMAP1 small ArfGAP 1 2.15823
VENTX VENT homeobox 2.15787
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 2.15728
EIF5A2 eukaryotic translation initiation factor 5A2 2.15727
CRELD2 cysteine-rich with EGF-like domains 2 2.15551
NCK2 NCK adaptor protein 2 2.15419
FGF20 fibroblast growth factor 20 2.15226
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 2.15139
PLA2G2E phospholipase A2, group IIE 2.1513
CD101 CD101 molecule 2.14936
MMP24 matrix metallopeptidase 24 (membrane-inserted) 2.14845
TPO thyroid peroxidase 2.14784
CEP131 centrosomal protein 131kDa 2.14599
CSRP1 cysteine and glycine-rich protein 1 2.14514
TRIM36 tripartite motif containing 36 2.14459
FOSL1 FOS-like antigen 1 2.14269
LRTM1 leucine-rich repeats and transmembrane domains 1 2.14227
KLF11 Kruppel-like factor 11 2.14077
KANK3 KN motif and ankyrin repeat domains 3 2.13913
LRRC15 leucine rich repeat containing 15 2.13883
DDX49 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 2.13815
GNB5 guanine nucleotide binding protein (G protein), beta 5 2.13729
PKP1 plakophilin 1 2.13533
TUBA4B tubulin, alpha 4b 2.13509
KRT35 keratin 35, type I 2.13342
RNF115 ring finger protein 115 2.13327
DKK4 dickkopf WNT signaling pathway inhibitor 4 2.13284
ZNF549 zinc finger protein 549 2.13202
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 2.13156
FMNL3 formin-like 3 2.13153
AGER advanced glycosylation end product-specific receptor 2.12982
UBE2A ubiquitin-conjugating enzyme E2A 2.12622
PODNL1 podocan-like 1 2.12508
STX3 syntaxin 3 2.12496
KMT5A lysine methyltransferase 5A 2.12261
PLIN2 perilipin 2 2.1221
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 2.12203
FRMPD1 FERM and PDZ domain containing 1 2.1211
PYGO1 pygopus family PHD finger 1 2.11993
NTN3 netrin 3 2.1182
SLC38A12 solute carrier family 38 member 12 2.11797
TACR3 tachykinin receptor 3 2.11651
MTSS1 metastasis suppressor 1 2.11589
H2BC17 H2B clustered histone 17 2.11385
MANF mesencephalic astrocyte-derived neurotrophic factor 2.11303
KPLCE KPRP N-terminal and LCE C-terminal like protein 2.11218
DGUOK deoxyguanosine kinase 2.10975
GAGE1 G antigen 1 2.1094
CHRM3 cholinergic receptor, muscarinic 3 2.10848
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.10788
H2BC11 H2B clustered histone 11 2.1074
DUSP14 dual specificity phosphatase 14 2.10696
WWC2 WW and C2 domain containing 2 2.10487
UCMA upper zone of growth plate and cartilage matrix associated 2.1036
ZIC1 Zic family member 1 2.10247
CBARP CACN subunit beta associated regulatory protein 2.10243
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2 2.10206
PDIA6 protein disulfide isomerase family A, member 6 2.1008
YBX1 Y box binding protein 1 2.10065
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 2.10042
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 2.09983
GNG11 guanine nucleotide binding protein (G protein), gamma 11 2.09701
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) 2.09588
MPL MPL proto-oncogene, thrombopoietin receptor 2.09549
DNMBP dynamin binding protein 2.09532
SIM2 single-minded family bHLH transcription factor 2 2.09304
SLAMF8 SLAM family member 8 2.09275
TMEM51 transmembrane protein 51 2.09194
CDCP1 CUB domain containing protein 1 2.0896
LAG3 lymphocyte-activation gene 3 2.08753
RXFP3 relaxin/insulin-like family peptide receptor 3 2.08575
SLC5A4 solute carrier family 5 (glucose activated ion channel), member 4 2.08517
CREB3L1 cAMP responsive element binding protein 3-like 1 2.08426
ACVRL1 activin A receptor type II-like 1 2.08358
COPS6 COP9 signalosome subunit 6 2.08354
CSRNP2 cysteine-serine-rich nuclear protein 2 2.08218
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 2.07717
CNMD chondromodulin 2.07668
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 2.07614
MSMB microseminoprotein, beta- 2.07574
TDRKH tudor and KH domain containing 2.07447
COL10A1 collagen, type X, alpha 1 2.07255
KISS1 KiSS-1 metastasis-suppressor 2.0705
AANAT aralkylamine N-acetyltransferase 2.06905
RAB1A RAB1A, member RAS oncogene family 2.06865
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) 2.06816
NRG1 neuregulin 1 2.06506
DCC DCC netrin 1 receptor 2.0646
PRAMEF10 PRAME family member 10 2.06258
EPHA7 EPH receptor A7 2.05657
STYXL1 serine/threonine/tyrosine interacting-like 1 2.05649
BRSK2 BR serine/threonine kinase 2 2.05523
GABPB1 GA binding protein transcription factor, beta subunit 1 2.05392
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 2.05176
TSPAN13 tetraspanin 13 2.05153
GPR3 G protein-coupled receptor 3 2.04954
H1-4 H1.4 linker histone, cluster member 2.0483
HTATSF1 HIV-1 Tat specific factor 1 2.04663
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 2.04625
NR4A2 nuclear receptor subfamily 4, group A, member 2 2.04253
TMEM204 transmembrane protein 204 2.04201
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 2.03982
RNF25 ring finger protein 25 2.03829
GUCY2F guanylate cyclase 2F, retinal 2.03808
KIF26B kinesin family member 26B 2.03795
ELMO1 engulfment and cell motility 1 2.0371
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) 2.03657
JCAD junctional cadherin 5 associated 2.03647
ZC3H7A zinc finger CCCH-type containing 7A 2.03605
EMILIN2 elastin microfibril interfacer 2 2.03584
COMMD9 COMM domain containing 9 2.0357
COL13A1 collagen, type XIII, alpha 1 2.0353
ADAM19 ADAM metallopeptidase domain 19 2.03394
DOCK2 dedicator of cytokinesis 2 2.03341
CAV1 caveolin 1, caveolae protein, 22kDa 2.03278
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 2.0323
UPK2 uroplakin 2 2.02865
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 2.02841
NTAN1 N-terminal asparagine amidase 2.02547
PDZRN4 PDZ domain containing ring finger 4 2.02539
POP7 processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) 2.02326
RGCC regulator of cell cycle 2.02024
HAND1 heart and neural crest derivatives expressed 1 2.02022
VSTM4 V-set and transmembrane domain containing 4 2.01997
PAX8 paired box 8 2.01864
CDC25A cell division cycle 25A 2.01864
FOXB1 forkhead box B1 2.01831
EDN3 endothelin 3 2.01818
TRPC7 transient receptor potential cation channel, subfamily C, member 7 2.01775
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II 2.01694
DOK4 docking protein 4 2.01683
CLTB clathrin, light chain B 2.01389
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.0128
MUC7 mucin 7, secreted 2.01254
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 2.01174
TNF tumor necrosis factor 2.00915
ASXL3 additional sex combs like transcriptional regulator 3 2.00765
TBCB tubulin folding cofactor B 2.0073
PHACTR2 phosphatase and actin regulator 2 2.00714
AUP1 ancient ubiquitous protein 1 2.00689
NEUROD1 neuronal differentiation 1 2.00625
PPDPF pancreatic progenitor cell differentiation and proliferation factor 2.00514
ATP1B4 ATPase, Na+/K+ transporting, beta 4 polypeptide 2.00479
AARSD1 alanyl-tRNA synthetase domain containing 1 2.00452
GDI1 GDP dissociation inhibitor 1 2.00372
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 2.0017
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.00012

decreased expression

Symbol Name Standardized Value
DDIT4 DNA-damage-inducible transcript 4 -9.02288
MSMO1 methylsterol monooxygenase 1 -8.91341
DCK deoxycytidine kinase -6.45571
HEATR1 HEAT repeat containing 1 -6.36162
COG2 component of oligomeric golgi complex 2 -6.33106
CPNE3 copine III -6.27601
TARBP1 TAR (HIV-1) RNA binding protein 1 -5.87284
B4GAT1 beta-1,4-glucuronyltransferase 1 -5.58935
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -5.50202
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -5.47713
ADI1 acireductone dioxygenase 1 -5.19264
CD58 CD58 molecule -5.10998
YME1L1 YME1-like 1 ATPase -4.82154
KHDC4 KH domain containing 4, pre-mRNA splicing factor -4.74229
PCCB propionyl CoA carboxylase, beta polypeptide -4.56983
TOP2A topoisomerase (DNA) II alpha 170kDa -4.50015
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -4.40872
S100A4 S100 calcium binding protein A4 -4.39323
TSPAN6 tetraspanin 6 -4.36323
TMEM267 transmembrane protein 267 -4.33334
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -4.30598
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -4.28442
PRKCD protein kinase C, delta -4.22991
SKIC2 SKI2 subunit of superkiller complex -4.18985
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -4.14725
ACBD4 acyl-CoA binding domain containing 4 -4.12171
OXCT1 3-oxoacid CoA transferase 1 -4.0474
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -4.02489
HOXA5 homeobox A5 -3.98386
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -3.9669
CHL1 cell adhesion molecule L1-like -3.96162
RPA3 replication protein A3, 14kDa -3.94536
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 -3.90482
NRIP1 nuclear receptor interacting protein 1 -3.88493
PRCP prolylcarboxypeptidase (angiotensinase C) -3.86232
GTPBP8 GTP-binding protein 8 (putative) -3.84409
LDHD lactate dehydrogenase D -3.72827
C2CD5 C2 calcium-dependent domain containing 5 -3.72134
HMG20B high mobility group 20B -3.67925
PPIC peptidylprolyl isomerase C (cyclophilin C) -3.67583
INSIG1 insulin induced gene 1 -3.66791
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -3.59218
FPGS folylpolyglutamate synthase -3.58583
TCTA T-cell leukemia translocation altered -3.56789
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -3.55545
FGGY FGGY carbohydrate kinase domain containing -3.53679
EXTL2 exostosin-like glycosyltransferase 2 -3.5295
MOAP1 modulator of apoptosis 1 -3.51731
TSC22D3 TSC22 domain family, member 3 -3.51535
BTN3A1 butyrophilin, subfamily 3, member A1 -3.50092
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 -3.49957
CDK1 cyclin-dependent kinase 1 -3.49137
ZNF451 zinc finger protein 451 -3.47793
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -3.46202
CASC3 cancer susceptibility candidate 3 -3.45485
ORAI3 ORAI calcium release-activated calcium modulator 3 -3.41491
EXOC1 exocyst complex component 1 -3.36601
FBXO34 F-box protein 34 -3.35663
NUP133 nucleoporin 133kDa -3.32904
TMEM186 transmembrane protein 186 -3.31543
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -3.31165
CBR4 carbonyl reductase 4 -3.2966
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D -3.29216
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein -3.28549
SREBF1 sterol regulatory element binding transcription factor 1 -3.2411
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 -3.21926
MRPS30 mitochondrial ribosomal protein S30 -3.2044
ATMIN ATM interactor -3.18827
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -3.16501
MYO5C myosin VC -3.16295
SNX2 sorting nexin 2 -3.1594
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -3.14208
CRTAP cartilage associated protein -3.13797
MX2 MX dynamin-like GTPase 2 -3.12832
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -3.11784
CISD1 CDGSH iron sulfur domain 1 -3.10991
TFB2M transcription factor B2, mitochondrial -3.10171
TOMM70 translocase of outer mitochondrial membrane 70 -3.08227
TSNAX translin-associated factor X -3.06656
CGRRF1 cell growth regulator with ring finger domain 1 -3.05626
ATRIP ATR interacting protein -3.05122
TRIM52 tripartite motif containing 52 -3.04415
CST3 cystatin C -3.03133
REPIN1 replication initiator 1 -3.01803
SYNE2 spectrin repeat containing, nuclear envelope 2 -3.01173
ADAR adenosine deaminase, RNA-specific -3.00582
LYRM1 LYR motif containing 1 -3.00466
MFN1 mitofusin 1 -3.0029
CREG1 cellular repressor of E1A-stimulated genes 1 -2.99363
AFG3L2 AFG3-like AAA ATPase 2 -2.98113
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.97127
RHOT1 ras homolog family member T1 -2.97113
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -2.96337
DENND2D DENN/MADD domain containing 2D -2.95942
ITGB8 integrin, beta 8 -2.94371
TMPRSS11D transmembrane protease, serine 11D -2.92771
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase -2.92656
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -2.90646
TRAPPC8 trafficking protein particle complex 8 -2.90529
NAMPT nicotinamide phosphoribosyltransferase -2.90299
PGM1 phosphoglucomutase 1 -2.88583
DCAF8 DDB1 and CUL4 associated factor 8 -2.88488
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.88395
PISD phosphatidylserine decarboxylase -2.8817
POLR2M polymerase (RNA) II (DNA directed) polypeptide M -2.87605
CYFIP2 cytoplasmic FMR1 interacting protein 2 -2.87128
NPR1 natriuretic peptide receptor 1 -2.86592
USP19 ubiquitin specific peptidase 19 -2.86238
WDR5B WD repeat domain 5B -2.86204
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 -2.84832
CR2 complement component (3d/Epstein Barr virus) receptor 2 -2.84181
SLC35A5 solute carrier family 35, member A5 -2.83827
TMEM187 transmembrane protein 187 -2.83582
CLTC clathrin, heavy chain (Hc) -2.83518
INTS3 integrator complex subunit 3 -2.8321
BBS4 Bardet-Biedl syndrome 4 -2.83156
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -2.83031
PLS1 plastin 1 -2.82815
PSRC1 proline/serine-rich coiled-coil 1 -2.82519
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 -2.81966
NIPSNAP1 nipsnap homolog 1 (C. elegans) -2.81644
XPO1 exportin 1 -2.81372
NLRP4 NLR family, pyrin domain containing 4 -2.81324
MSL1 male-specific lethal 1 homolog (Drosophila) -2.8098
EPHA1 EPH receptor A1 -2.79434
NIPSNAP2 nipsnap homolog 2 -2.79391
MFF mitochondrial fission factor -2.78524
CD320 CD320 molecule -2.78416
NEK7 NIMA-related kinase 7 -2.78068
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -2.77516
RNPEP arginyl aminopeptidase (aminopeptidase B) -2.77206
UBXN2B UBX domain protein 2B -2.76246
NPEPPS aminopeptidase puromycin sensitive -2.75142
UQCRFS1 ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 -2.74023
PCYT2 phosphate cytidylyltransferase 2, ethanolamine -2.73845
INTS14 integrator complex subunit 14 -2.73719
TSKU tsukushi, small leucine rich proteoglycan -2.73444
ABI3BP ABI family, member 3 (NESH) binding protein -2.73412
PRUNE1 prune exopolyphosphatase 1 -2.7326
GOLPH3L golgi phosphoprotein 3-like -2.72053
COG7 component of oligomeric golgi complex 7 -2.7028
NNT nicotinamide nucleotide transhydrogenase -2.70268
PALB2 partner and localizer of BRCA2 -2.69669
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.6963
SHPK sedoheptulokinase -2.69518
PRR15L proline rich 15-like -2.68864
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) -2.68152
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.68029
EPRS1 glutamyl-prolyl-tRNA synthetase 1 -2.67677
DMXL1 Dmx-like 1 -2.67574
CMTR1 cap methyltransferase 1 -2.67516
CD46 CD46 molecule, complement regulatory protein -2.673
UFL1 UFM1-specific ligase 1 -2.65954
PANK3 pantothenate kinase 3 -2.65679
PRDX5 peroxiredoxin 5 -2.65529
HACL2 2-hydroxyacyl-CoA lyase 2 -2.64991
PEX12 peroxisomal biogenesis factor 12 -2.64961
TRIM6-TRIM34 TRIM6-TRIM34 readthrough -2.64826
LOC124907090 ankyrin repeat domain-containing protein SOWAHC-like -2.64665
TCTN1 tectonic family member 1 -2.64404
FPGT fucose-1-phosphate guanylyltransferase -2.64181
HADH hydroxyacyl-CoA dehydrogenase -2.63939
GOLGB1 golgin B1 -2.62837
RETREG3 reticulophagy regulator family member 3 -2.62299
NHLRC2 NHL repeat containing 2 -2.61977
PPA2 pyrophosphatase (inorganic) 2 -2.61018
ITGA7 integrin, alpha 7 -2.60777
WRAP73 WD repeat containing, antisense to TP73 -2.6056
BTN3A2 butyrophilin, subfamily 3, member A2 -2.59762
EPS15 epidermal growth factor receptor pathway substrate 15 -2.59639
PROS1 protein S (alpha) -2.59584
AKAP10 A kinase (PRKA) anchor protein 10 -2.59567
TDRD7 tudor domain containing 7 -2.59306
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 -2.5928
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) -2.58529
MRPS27 mitochondrial ribosomal protein S27 -2.57966
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -2.57429
CSK c-src tyrosine kinase -2.57361
SPTSSA serine palmitoyltransferase, small subunit A -2.56654
KAT8 K(lysine) acetyltransferase 8 -2.55922
STK11 serine/threonine kinase 11 -2.54527
RCOR3 REST corepressor 3 -2.53598
FAM8A1 family with sequence similarity 8, member A1 -2.53554
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -2.53029
ELOVL6 ELOVL fatty acid elongase 6 -2.53025
SUOX sulfite oxidase -2.5298
SDR39U1 short chain dehydrogenase/reductase family 39U, member 1 -2.52371
CCNB2 cyclin B2 -2.51847
ZNF76 zinc finger protein 76 -2.51778
AP5M1 adaptor-related protein complex 5, mu 1 subunit -2.51637
NCOA4 nuclear receptor coactivator 4 -2.51565
FAM111A family with sequence similarity 111, member A -2.51465
TIPRL TOR signaling pathway regulator -2.51024
HMGN4 high mobility group nucleosomal binding domain 4 -2.50959
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.50891
NECAB3 N-terminal EF-hand calcium binding protein 3 -2.50758
CXCR2 chemokine (C-X-C motif) receptor 2 -2.5074
CABIN1 calcineurin binding protein 1 -2.50633
TMEM231 transmembrane protein 231 -2.50507
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.49928
TRAP1 TNF receptor-associated protein 1 -2.49606
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -2.49564
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 -2.49505
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -2.49233
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A -2.4887
BLVRB biliverdin reductase B -2.48469
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -2.47707
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 -2.47025
HOXB3 homeobox B3 -2.46997
EIF4EBP3 eukaryotic translation initiation factor 4E binding protein 3 -2.46869
ANGEL1 angel homolog 1 (Drosophila) -2.46619
KIF14 kinesin family member 14 -2.46438
PTER phosphotriesterase related -2.46097
TMEM168 transmembrane protein 168 -2.4607
ICE1 interactor of little elongation complex ELL subunit 1 -2.44609
DAAM1 dishevelled associated activator of morphogenesis 1 -2.44332
CTSO cathepsin O -2.43261
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like -2.43244
ZNF189 zinc finger protein 189 -2.43117
KYAT1 kynurenine aminotransferase 1 -2.43053
SNUPN snurportin 1 -2.42818
MMUT methylmalonyl-CoA mutase -2.42633
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -2.42461
NFIL3 nuclear factor, interleukin 3 regulated -2.42406
ACADSB acyl-CoA dehydrogenase, short/branched chain -2.4172
ARL17B ADP-ribosylation factor-like 17B -2.41601
ERI2 ERI1 exoribonuclease family member 2 -2.41251
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 -2.41186
SLC25A2 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2 -2.40953
DPM3 dolichyl-phosphate mannosyltransferase polypeptide 3 -2.40448
NCAPD2 non-SMC condensin I complex, subunit D2 -2.40098
PUM2 pumilio RNA-binding family member 2 -2.39896
MAP2K5 mitogen-activated protein kinase kinase 5 -2.39624
JADE2 jade family PHD finger 2 -2.39548
EPM2AIP1 EPM2A (laforin) interacting protein 1 -2.39357
RANBP10 RAN binding protein 10 -2.3896
ARHGAP12 Rho GTPase activating protein 12 -2.38666
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 -2.38605
SLC35E2B solute carrier family 35, member E2B -2.38423
TGM1 transglutaminase 1 -2.38205
PNPLA3 patatin-like phospholipase domain containing 3 -2.38191
RBM47 RNA binding motif protein 47 -2.37622
PRMT3 protein arginine methyltransferase 3 -2.37379
MRPS14 mitochondrial ribosomal protein S14 -2.36948
GCLC glutamate-cysteine ligase, catalytic subunit -2.36517
ATXN7L3B ataxin 7-like 3B -2.36136
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 -2.36079
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.35688
PHKB phosphorylase kinase, beta -2.35544
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -2.35511
H2AC25 H2A clustered histone 25 -2.35439
PTK2 protein tyrosine kinase 2 -2.35262
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 -2.35205
SDAD1 SDA1 domain containing 1 -2.34931
CDC25B cell division cycle 25B -2.34841
PRSS8 protease, serine, 8 -2.34753
AHR aryl hydrocarbon receptor -2.34648
RNF123 ring finger protein 123 -2.34642
XPO6 exportin 6 -2.3448
FLOT2 flotillin 2 -2.34309
SRP9 signal recognition particle 9kDa -2.34296
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -2.33694
GCAT glycine C-acetyltransferase -2.33417
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -2.33327
SIAH2 siah E3 ubiquitin protein ligase 2 -2.32895
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) -2.32768
FAM114A2 family with sequence similarity 114, member A2 -2.32672
TMEM33 transmembrane protein 33 -2.3226
PEX19 peroxisomal biogenesis factor 19 -2.32168
FOXO3 forkhead box O3 -2.31935
SLC30A9 solute carrier family 30 (zinc transporter), member 9 -2.3184
NOC3L nucleolar complex associated 3 homolog (S. cerevisiae) -2.31661
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 -2.3164
TFB1M transcription factor B1, mitochondrial -2.31634
ANKRD17 ankyrin repeat domain 17 -2.31497
ING4 inhibitor of growth family, member 4 -2.31098
MINDY1 MINDY lysine 48 deubiquitinase 1 -2.31056
FAM193B family with sequence similarity 193, member B -2.31049
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -2.30576
SPA17 sperm autoantigenic protein 17 -2.30517
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -2.30392
PNISR PNN-interacting serine/arginine-rich protein -2.29889
DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 -2.29798
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit -2.29674
ATM ATM serine/threonine kinase -2.29529
URGCP upregulator of cell proliferation -2.29514
EAPP E2F-associated phosphoprotein -2.29391
CLOCK clock circadian regulator -2.29142
ASPA aspartoacylase -2.28603
AKAP11 A kinase (PRKA) anchor protein 11 -2.28487
PELI2 pellino E3 ubiquitin protein ligase family member 2 -2.28353
LCMT2 leucine carboxyl methyltransferase 2 -2.28175
ST20-MTHFS ST20-MTHFS readthrough -2.28108
BAZ2B bromodomain adjacent to zinc finger domain, 2B -2.27921
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) -2.27892
CHIC2 cysteine-rich hydrophobic domain 2 -2.27647
NLRP2B NLR family pyrin domain containing 2B -2.27524
TASOR transcription activation suppressor -2.27136
PILRB paired immunoglobin-like type 2 receptor beta -2.27072
TUFM Tu translation elongation factor, mitochondrial -2.27019
KLK6 kallikrein-related peptidase 6 -2.26939
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 -2.2665
ACY1 aminoacylase 1 -2.26057
IFITM3 interferon induced transmembrane protein 3 -2.26001
ZNF322 zinc finger protein 322 -2.25953
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 -2.25511
MVD mevalonate (diphospho) decarboxylase -2.25437
CCNA2 cyclin A2 -2.25242
NARS1 asparaginyl-tRNA synthetase 1 -2.25182
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 -2.2506
CXCL6 chemokine (C-X-C motif) ligand 6 -2.25049
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 -2.2502
TBC1D10C TBC1 domain family, member 10C -2.24927
SCAP SREBF chaperone -2.24536
SMAD5 SMAD family member 5 -2.24485
HSDL2 hydroxysteroid dehydrogenase like 2 -2.24141
COX15 cytochrome c oxidase assembly homolog 15 (yeast) -2.23792
ZNF12 zinc finger protein 12 -2.23405
NIP7 NIP7, nucleolar pre-rRNA processing protein -2.23364
CPOX coproporphyrinogen oxidase -2.23266
SPG11 spastic paraplegia 11 (autosomal recessive) -2.22956
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -2.22657
PARG poly (ADP-ribose) glycohydrolase -2.22321
USP18 ubiquitin specific peptidase 18 -2.22151
PTGES prostaglandin E synthase -2.22085
CCNG1 cyclin G1 -2.22032
MAT2A methionine adenosyltransferase II, alpha -2.22004
S100A12 S100 calcium binding protein A12 -2.21817
PARP4 poly (ADP-ribose) polymerase family, member 4 -2.21685
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) -2.21596
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa -2.21553
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein -2.21441
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -2.20687
ACTMAP actin maturation protease -2.20507
ANKRD10 ankyrin repeat domain 10 -2.2046
ACSL3 acyl-CoA synthetase long-chain family member 3 -2.20406
RBL2 retinoblastoma-like 2 -2.20327
THTPA thiamine triphosphatase -2.20049
MSRB1 methionine sulfoxide reductase B1 -2.19594
SYBU syntabulin (syntaxin-interacting) -2.19574
TLR3 toll-like receptor 3 -2.19572
PDF peptide deformylase (mitochondrial) -2.19193
MNAT1 MNAT CDK-activating kinase assembly factor 1 -2.1915
IFITM2 interferon induced transmembrane protein 2 -2.19029
OXA1L oxidase (cytochrome c) assembly 1-like -2.18922
INTS5 integrator complex subunit 5 -2.18831
STXBP3 syntaxin binding protein 3 -2.18183
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -2.18179
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 -2.1812
PIPOX pipecolic acid oxidase -2.18074
UNC50 unc-50 homolog (C. elegans) -2.17987
BBS10 Bardet-Biedl syndrome 10 -2.17985
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae) -2.17768
GLRX5 glutaredoxin 5 -2.17711
TYW2 tRNA wybutosine-synthesizing protein 2 -2.17465
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) -2.17354
IFT46 intraflagellar transport 46 -2.17236
ZNF384 zinc finger protein 384 -2.16888
SHOC2 soc-2 suppressor of clear homolog (C. elegans) -2.16815
MAT2B methionine adenosyltransferase II, beta -2.16747
DHRS11 dehydrogenase/reductase (SDR family) member 11 -2.16519
SYPL1 synaptophysin-like 1 -2.16363
AUH AU RNA binding protein/enoyl-CoA hydratase -2.16151
PIGV phosphatidylinositol glycan anchor biosynthesis, class V -2.16102
PIGF phosphatidylinositol glycan anchor biosynthesis, class F -2.16093
CRYL1 crystallin, lambda 1 -2.16008
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -2.15908
SUB1 SUB1 homolog (S. cerevisiae) -2.15778
SKAP2 src kinase associated phosphoprotein 2 -2.15522
MGST2 microsomal glutathione S-transferase 2 -2.1536
ARHGAP9 Rho GTPase activating protein 9 -2.15347
MYO18A myosin XVIIIA -2.15329
KCTD3 potassium channel tetramerization domain containing 3 -2.15233
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -2.15228
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -2.15045
FASTKD1 FAST kinase domains 1 -2.14828
KLHDC2 kelch domain containing 2 -2.14713
CDC23 cell division cycle 23 -2.14622
MPPE1 metallophosphoesterase 1 -2.1372
TTC38 tetratricopeptide repeat domain 38 -2.13605
NPIPB5 nuclear pore complex interacting protein family, member B5 -2.13504
FBXO46 F-box protein 46 -2.13228
CLDND1 claudin domain containing 1 -2.13202
GNPAT glyceronephosphate O-acyltransferase -2.13194
DNM1 dynamin 1 -2.13156
RXRA retinoid X receptor, alpha -2.13132
FZD4 frizzled class receptor 4 -2.12898
UBXN6 UBX domain protein 6 -2.12811
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.12763
UBE2H ubiquitin-conjugating enzyme E2H -2.12681
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -2.12421
SKP1 S-phase kinase-associated protein 1 -2.12347
OSBPL8 oxysterol binding protein-like 8 -2.12213
MRPL34 mitochondrial ribosomal protein L34 -2.11253
ZNF318 zinc finger protein 318 -2.10879
APOLD1 apolipoprotein L domain containing 1 -2.10844
LRRC20 leucine rich repeat containing 20 -2.10401
NUBPL nucleotide binding protein-like -2.10346
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) -2.10276
TLK2 tousled-like kinase 2 -2.10266
GYS1 glycogen synthase 1 (muscle) -2.10233
ZNF148 zinc finger protein 148 -2.10089
METTL4 methyltransferase like 4 -2.09972
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.09832
SORT1 sortilin 1 -2.0965
ZNF226 zinc finger protein 226 -2.09279
RNF139 ring finger protein 139 -2.08914
LPAR2 lysophosphatidic acid receptor 2 -2.08767
TRAPPC11 trafficking protein particle complex 11 -2.08568
LTN1 listerin E3 ubiquitin protein ligase 1 -2.084
RAB5IF RAB5 interacting factor -2.08274
TMEM80 transmembrane protein 80 -2.08038
LYPLA1 lysophospholipase I -2.0784
MARCHF7 membrane associated ring-CH-type finger 7 -2.07786
PAIP1 poly(A) binding protein interacting protein 1 -2.07615
PTAFR platelet-activating factor receptor -2.07544
ICE2 interactor of little elongation complex ELL subunit 2 -2.07351
ABHD10 abhydrolase domain containing 10 -2.0733
MTREX Mtr4 exosome RNA helicase -2.07213
CKAP5 cytoskeleton associated protein 5 -2.07198
NEK9 NIMA-related kinase 9 -2.07125
MPZL1 myelin protein zero-like 1 -2.06889
TK2 thymidine kinase 2, mitochondrial -2.06873
COASY CoA synthase -2.06863
FOXC1 forkhead box C1 -2.06795
DHCR7 7-dehydrocholesterol reductase -2.06695
MZF1 myeloid zinc finger 1 -2.06325
LAMC1 laminin, gamma 1 (formerly LAMB2) -2.05924
TMEM135 transmembrane protein 135 -2.05824
USP33 ubiquitin specific peptidase 33 -2.05771
GPC3 glypican 3 -2.05586
CAVIN2 caveolae associated protein 2 -2.05546
MXI1 MAX interactor 1, dimerization protein -2.05449
CDK4 cyclin-dependent kinase 4 -2.05411
GPSM3 G-protein signaling modulator 3 -2.05256
ETV4 ets variant 4 -2.04959
CPT2 carnitine palmitoyltransferase 2 -2.04904
TUBGCP4 tubulin, gamma complex associated protein 4 -2.04794
KAT2A K(lysine) acetyltransferase 2A -2.04789
CEP192 centrosomal protein 192kDa -2.04493
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -2.04428
SLC41A3 solute carrier family 41, member 3 -2.04287
CEP350 centrosomal protein 350kDa -2.04215
FBXO7 F-box protein 7 -2.04076
MKLN1 muskelin 1, intracellular mediator containing kelch motifs -2.03877
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -2.0372
ZNF83 zinc finger protein 83 -2.03717
MGAM maltase-glucoamylase -2.03515
AGAP4 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4 -2.03509
DSN1 DSN1, MIS12 kinetochore complex component -2.03351
RNF44 ring finger protein 44 -2.03227
SSBP2 single-stranded DNA binding protein 2 -2.03205
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 -2.0303
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic) -2.03023
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 -2.03018
ADNP activity-dependent neuroprotector homeobox -2.02982
CIC capicua transcriptional repressor -2.0276
DGAT1 diacylglycerol O-acyltransferase 1 -2.02259
FBXL2 F-box and leucine-rich repeat protein 2 -2.02015
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 -2.02004
NME5 NME/NM23 family member 5 -2.01925
ACP6 acid phosphatase 6, lysophosphatidic -2.01881
LOC124907837 sulfotransferase 1A3 -2.01801
GSTK1 glutathione S-transferase kappa 1 -2.01756
ISCU iron-sulfur cluster assembly enzyme -2.0119
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) -2.01157
SPATA6 spermatogenesis associated 6 -2.00998
CRBN cereblon -2.00957
SERF1A small EDRK-rich factor 1A (telomeric) -2.00252
KDM5A lysine (K)-specific demethylase 5A -2.00129