CRCGN016_MCF10A.WT.HP_24H:F15 Gene Set
Genes
43 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:F15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
5.59007
|
|
KLHL21
|
kelch-like family member 21
|
5.47418
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
5.11074
|
|
CHEK1
|
checkpoint kinase 1
|
4.46978
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.47019
|
|
WDR7
|
WD repeat domain 7
|
3.16399
|
|
WFS1
|
Wolfram syndrome 1 (wolframin)
|
3.1533
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.84573
|
|
MVP
|
major vault protein
|
2.7569
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.73415
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.57709
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
2.20358
|
|
HAS2
|
hyaluronan synthase 2
|
2.20183
|
|
IL36G
|
interleukin 36, gamma
|
2.13064
|
|
ANGPT1
|
angiopoietin 1
|
2.11015
|
|
LILRA4
|
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
|
2.03499
|
|
SERPINE1
|
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
|
2.01779
|
|
RPS6KA3
|
ribosomal protein S6 kinase, 90kDa, polypeptide 3
|
2.00465
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
-5.66779
|
|
SORBS3
|
sorbin and SH3 domain containing 3
|
-4.86086
|
|
PARP2
|
poly (ADP-ribose) polymerase 2
|
-4.44644
|
|
PIK3C2B
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
|
-3.47631
|
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-3.26984
|
|
HEATR1
|
HEAT repeat containing 1
|
-3.18647
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-2.9197
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.79851
|
|
OSGEP
|
O-sialoglycoprotein endopeptidase
|
-2.73227
|
|
IPO13
|
importin 13
|
-2.47479
|
|
PCDHGA5
|
protocadherin gamma subfamily A, 5
|
-2.45946
|
|
METTL17
|
methyltransferase like 17
|
-2.43415
|
|
SCYL3
|
SCY1-like 3 (S. cerevisiae)
|
-2.43392
|
|
INTS15
|
integrator complex subunit 15
|
-2.41166
|
|
CHD8
|
chromodomain helicase DNA binding protein 8
|
-2.31684
|
|
NCAPD2
|
non-SMC condensin I complex, subunit D2
|
-2.24328
|
|
RBM23
|
RNA binding motif protein 23
|
-2.23326
|
|
STRN4
|
striatin, calmodulin binding protein 4
|
-2.17519
|
|
MCPH1
|
microcephalin 1
|
-2.14588
|
|
TOPORS
|
topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
|
-2.10443
|
|
DEAF1
|
DEAF1 transcription factor
|
-2.08032
|
|
APMAP
|
adipocyte plasma membrane associated protein
|
-2.07671
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.074
|
|
ZNF35
|
zinc finger protein 35
|
-2.05835
|
|
TTC9
|
tetratricopeptide repeat domain 9
|
-2.03281
|
