| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | BRD-K88965984 100.97 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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93 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:F16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EPHB2 | EPH receptor B2 | 4.84069 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 4.53327 |
| CNPY3 | canopy FGF signaling regulator 3 | 4.23147 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 4.15551 |
| COMP | cartilage oligomeric matrix protein | 3.54345 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 3.44411 |
| LGALS8 | lectin, galactoside-binding, soluble, 8 | 3.38741 |
| SLC11A2 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 | 3.38151 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 3.29618 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 3.16573 |
| BAX | BCL2-associated X protein | 3.08512 |
| AARS1 | alanyl-tRNA synthetase 1 | 3.02393 |
| TSKU | tsukushi, small leucine rich proteoglycan | 2.8295 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 2.77165 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 | 2.65316 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 2.64133 |
| CD53 | CD53 molecule | 2.61898 |
| ZNF692 | zinc finger protein 692 | 2.57384 |
| EML3 | echinoderm microtubule associated protein like 3 | 2.56464 |
| SCRN1 | secernin 1 | 2.49165 |
| C1QA | complement component 1, q subcomponent, A chain | 2.46915 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 2.45605 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 2.43 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.41011 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit | 2.38157 |
| CAPNS1 | calpain, small subunit 1 | 2.34916 |
| DNM1 | dynamin 1 | 2.27504 |
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 2.2636 |
| ZNF589 | zinc finger protein 589 | 2.25021 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 2.22599 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | 2.21373 |
| LAPTM5 | lysosomal protein transmembrane 5 | 2.20869 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 2.19952 |
| C1QB | complement component 1, q subcomponent, B chain | 2.19575 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | 2.19142 |
| LMNB1 | lamin B1 | 2.18295 |
| ATP5MC1 | ATP synthase membrane subunit c locus 1 | 2.16066 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 | 2.15837 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) | 2.14412 |
| DENND4B | DENN/MADD domain containing 4B | 2.14067 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 2.11882 |
| MAVS | mitochondrial antiviral signaling protein | 2.11556 |
| KPTN | kaptin (actin binding protein) | 2.09991 |
| METTL3 | methyltransferase like 3 | 2.07368 |
| ADRB2 | adrenoceptor beta 2, surface | 2.06193 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | 2.04728 |
| PDLIM1 | PDZ and LIM domain 1 | 2.04481 |
| PADI1 | peptidyl arginine deiminase, type I | 2.04108 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 | 2.01214 |
| CLEC16A | C-type lectin domain family 16, member A | 2.00915 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -5.55845 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -5.52357 |
| HMG20B | high mobility group 20B | -4.84773 |
| HAT1 | histone acetyltransferase 1 | -4.7171 |
| EXOSC4 | exosome component 4 | -3.78203 |
| MSMO1 | methylsterol monooxygenase 1 | -3.31891 |
| GDF15 | growth differentiation factor 15 | -3.16866 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.94534 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -2.93757 |
| RPN1 | ribophorin I | -2.91072 |
| MTFR1 | mitochondrial fission regulator 1 | -2.83931 |
| MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | -2.73073 |
| VDAC1 | voltage-dependent anion channel 1 | -2.72214 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -2.66628 |
| EI24 | etoposide induced 2.4 | -2.55787 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -2.52592 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | -2.47618 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -2.41156 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) | -2.38688 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | -2.32208 |
| MOK | MOK protein kinase | -2.31701 |
| SERPINA7 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 | -2.26505 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -2.24348 |
| CAB39 | calcium binding protein 39 | -2.2392 |
| NKAPD1 | NKAP domain containing 1 | -2.22487 |
| FKBP14 | FK506 binding protein 14, 22 kDa | -2.21066 |
| TBPL1 | TBP-like 1 | -2.20186 |
| PDE1A | phosphodiesterase 1A, calmodulin-dependent | -2.17161 |
| ILKAP | integrin-linked kinase-associated serine/threonine phosphatase | -2.15289 |
| GOLT1B | golgi transport 1B | -2.15059 |
| ANXA10 | annexin A10 | -2.14967 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.12786 |
| WAPL | WAPL cohesin release factor | -2.11275 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.1053 |
| DUSP6 | dual specificity phosphatase 6 | -2.10282 |
| DPY19L4 | dpy-19-like 4 (C. elegans) | -2.07997 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | -2.06882 |
| NANS | N-acetylneuraminic acid synthase | -2.04229 |
| PUF60 | poly-U binding splicing factor 60KDa | -2.04213 |
| MATCAP2 | microtubule associated tyrosine carboxypeptidase 2 | -2.02403 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -2.00795 |
| CNKSR3 | CNKSR family member 3 | -2.00514 |
| SREK1IP1 | SREK1-interacting protein 1 | -2.00041 |
