CRCGN016_MCF10A.WT.HP_24H:F17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description BRD-K88965984 33.66 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

35 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:F17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PEX11A peroxisomal biogenesis factor 11 alpha 5.15173
CXCL2 chemokine (C-X-C motif) ligand 2 4.97568
HBA1 hemoglobin, alpha 1 4.34487
CRELD2 cysteine-rich with EGF-like domains 2 4.24017
ABHD4 abhydrolase domain containing 4 3.63844
TBPL1 TBP-like 1 3.38836
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 3.3878
ADO 2-aminoethanethiol (cysteamine) dioxygenase 3.18027
ACAA1 acetyl-CoA acyltransferase 1 3.0326
AGR2 anterior gradient 2 2.98327
HBB hemoglobin, beta 2.72284
MYBPC1 myosin binding protein C, slow type 2.58563
ATXN10 ataxin 10 2.42785
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26 2.29686
CD1B CD1b molecule 2.1539
IMPACT impact RWD domain protein 2.10638
CTNND2 catenin (cadherin-associated protein), delta 2 2.10299
TRIL TLR4 interactor with leucine-rich repeats 2.06903
OSGIN2 oxidative stress induced growth inhibitor family member 2 2.04747
ECH1 enoyl CoA hydratase 1, peroxisomal 2.00807
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow 2.00556

decreased expression

Symbol Name Standardized Value
KIF14 kinesin family member 14 -3.45413
JMJD6 jumonji domain containing 6 -3.42485
NVL nuclear VCP-like -3.27731
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -3.18031
KRT14 keratin 14, type I -2.943
CNIH4 cornichon family AMPA receptor auxiliary protein 4 -2.87795
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.48795
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.23195
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.2109
FBXO28 F-box protein 28 -2.19813
KLF2 Kruppel-like factor 2 -2.15823
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.11666
EEF1B2 eukaryotic translation elongation factor 1 beta 2 -2.06594
DEGS1 delta(4)-desaturase, sphingolipid 1 -2.00286