CRCGN016_MCF10A.WT.HP_24H:F19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzo(a)pyrene 96.93 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

47 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:F19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCL2 chemokine (C-C motif) ligand 2 5.77723
PNKP polynucleotide kinase 3'-phosphatase 4.79837
PPARG peroxisome proliferator-activated receptor gamma 4.53236
ADO 2-aminoethanethiol (cysteamine) dioxygenase 4.23379
AGR2 anterior gradient 2 3.50351
TIAM1 T-cell lymphoma invasion and metastasis 1 2.81816
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.76177
CDC25B cell division cycle 25B 2.61569
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.42895
HAS2 hyaluronan synthase 2 2.38978
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.29371
NUTF2 nuclear transport factor 2 2.26779
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12 2.21008
ALAS1 5'-aminolevulinate synthase 1 2.19249
IL1B interleukin 1, beta 2.17388
TXNDC5 thioredoxin domain containing 5 (endoplasmic reticulum) 2.14713
PRR3 proline rich 3 2.04447
CDPF1 cysteine-rich, DPF motif domain containing 1 2.0045

decreased expression

Symbol Name Standardized Value
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -6.52713
NSDHL NAD(P) dependent steroid dehydrogenase-like -4.45093
CRK v-crk avian sarcoma virus CT10 oncogene homolog -4.39876
RNF167 ring finger protein 167 -3.76033
CHMP4B charged multivesicular body protein 4B -3.46998
BASP1 brain abundant, membrane attached signal protein 1 -3.16881
SORBS3 sorbin and SH3 domain containing 3 -2.79355
BPHL biphenyl hydrolase-like (serine hydrolase) -2.70171
KRT14 keratin 14, type I -2.64542
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9 -2.63285
ZNF430 zinc finger protein 430 -2.44678
CXCL9 chemokine (C-X-C motif) ligand 9 -2.39107
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -2.37864
TXNDC9 thioredoxin domain containing 9 -2.35625
IL18 interleukin 18 -2.29604
HLA-E major histocompatibility complex, class I, E -2.25611
HLA-F major histocompatibility complex, class I, F -2.23545
SCAND1 SCAN domain containing 1 -2.22804
TMEM184C transmembrane protein 184C -2.2211
FLCN folliculin -2.19704
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -2.16307
INKA2 inka box actin regulator 2 -2.12145
INPP5K inositol polyphosphate-5-phosphatase K -2.07879
STAT1 signal transducer and activator of transcription 1, 91kDa -2.03586
MSMO1 methylsterol monooxygenase 1 -2.02312
SREK1IP1 SREK1-interacting protein 1 -2.02268
CPM carboxypeptidase M -2.01649
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -2.01604
SLC25A44 solute carrier family 25, member 44 -2.00265