CRCGN016_MCF10A.WT.HP_24H:F20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description benzo(a)pyrene 32.31 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

49 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:F20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CASP2 caspase 2, apoptosis-related cysteine peptidase 7.41436
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 4.80742
MTA2 metastasis associated 1 family, member 2 4.64887
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 4.49112
EPHB2 EPH receptor B2 3.93405
HBA1 hemoglobin, alpha 1 3.60863
SPDEF SAM pointed domain containing ETS transcription factor 3.44827
HBB hemoglobin, beta 3.43166
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 3.41094
NUTF2 nuclear transport factor 2 3.11505
CCNF cyclin F 2.99008
HNRNPL heterogeneous nuclear ribonucleoprotein L 2.98233
C2CD2 C2 calcium-dependent domain containing 2 2.92184
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 2.89723
MDM4 MDM4, p53 regulator 2.84261
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 2.60419
CEPT1 choline/ethanolamine phosphotransferase 1 2.59775
ALAS1 5'-aminolevulinate synthase 1 2.53952
THRAP3 thyroid hormone receptor associated protein 3 2.50765
SATB1 SATB homeobox 1 2.48554
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 2.45405
STRN3 striatin, calmodulin binding protein 3 2.45114
CDPF1 cysteine-rich, DPF motif domain containing 1 2.37532
EIF5AL1 eukaryotic translation initiation factor 5A-like 1 2.22766
PRR3 proline rich 3 2.22064
GDF2 growth differentiation factor 2 2.18757
WDR76 WD repeat domain 76 2.14858
NECAB3 N-terminal EF-hand calcium binding protein 3 2.12661
TTC31 tetratricopeptide repeat domain 31 2.10661
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) 2.10121
RBBP5 retinoblastoma binding protein 5 2.06754
KIF5C kinesin family member 5C 2.0576
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 2.03042
SBNO1 strawberry notch homolog 1 (Drosophila) 2.01852

decreased expression

Symbol Name Standardized Value
CAB39 calcium binding protein 39 -4.86881
S100A8 S100 calcium binding protein A8 -4.73525
RPA3 replication protein A3, 14kDa -4.66531
THAP11 THAP domain containing 11 -4.21833
SLC35F2 solute carrier family 35, member F2 -3.301
TIMP1 TIMP metallopeptidase inhibitor 1 -3.06164
PCNA proliferating cell nuclear antigen -2.92355
KIF14 kinesin family member 14 -2.4739
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.28193
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -2.14023
PRELID3A PRELI domain containing 3A -2.10462
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -2.09078
TFF2 trefoil factor 2 -2.07916
CHMP2A charged multivesicular body protein 2A -2.02379
MAP9 microtubule-associated protein 9 -2.01757