CRCGN016_MCF10A.WT.HP_24H:F24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-methylaniline 11.18 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

28 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:F24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CASP2 caspase 2, apoptosis-related cysteine peptidase 4.32551
COMP cartilage oligomeric matrix protein 2.88444
NUTF2 nuclear transport factor 2 2.85787
MDM4 MDM4, p53 regulator 2.68783
MTA2 metastasis associated 1 family, member 2 2.40778
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 2.40538
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.35761
AGR2 anterior gradient 2 2.33438
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.28515
HNRNPL heterogeneous nuclear ribonucleoprotein L 2.25383
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.12453
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 2.0989
KIF5C kinesin family member 5C 2.08526
TCEAL4 transcription elongation factor A (SII)-like 4 2.01018

decreased expression

Symbol Name Standardized Value
SLC35F2 solute carrier family 35, member F2 -4.81297
HMG20B high mobility group 20B -4.00998
SCYL3 SCY1-like 3 (S. cerevisiae) -3.69504
OXA1L oxidase (cytochrome c) assembly 1-like -3.67866
DERA deoxyribose-phosphate aldolase (putative) -3.55045
LYPLA1 lysophospholipase I -3.43242
KDM3A lysine (K)-specific demethylase 3A -3.21999
TXNDC9 thioredoxin domain containing 9 -2.98955
BPHL biphenyl hydrolase-like (serine hydrolase) -2.90527
COG2 component of oligomeric golgi complex 2 -2.33801
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -2.32952
RPIA ribose 5-phosphate isomerase A -2.32306
RNF167 ring finger protein 167 -2.27223
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -2.18872