| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | theophylline 101.98 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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63 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:G01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.92353 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 | 4.49946 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.74594 |
| TBPL1 | TBP-like 1 | 3.308 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 3.05988 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 3.00664 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.95717 |
| PNPO | pyridoxamine 5'-phosphate oxidase | 2.70006 |
| AGR2 | anterior gradient 2 | 2.59127 |
| C1QB | complement component 1, q subcomponent, B chain | 2.46585 |
| DENND2D | DENN/MADD domain containing 2D | 2.42274 |
| TCTA | T-cell leukemia translocation altered | 2.3582 |
| TRAPPC4 | trafficking protein particle complex 4 | 2.29533 |
| RGS2 | regulator of G-protein signaling 2 | 2.2651 |
| PRR7 | proline rich 7 (synaptic) | 2.2104 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 2.18409 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 2.15919 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 2.15671 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 2.08742 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.07442 |
| C1QA | complement component 1, q subcomponent, A chain | 2.07257 |
| THADA | thyroid adenoma associated | 2.06786 |
| MMP1 | matrix metallopeptidase 1 | 2.05598 |
| CP | ceruloplasmin (ferroxidase) | 2.0115 |
| RCE1 | Ras converting CAAX endopeptidase 1 | 2.00384 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DSG2 | desmoglein 2 | -5.16685 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | -5.07805 |
| TNIP1 | TNFAIP3 interacting protein 1 | -4.97917 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.89591 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.41493 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.81716 |
| RXYLT1 | ribitol xylosyltransferase 1 | -3.28873 |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 | -3.08416 |
| DNM1L | dynamin 1-like | -2.97977 |
| CNTN1 | contactin 1 | -2.90002 |
| KRT14 | keratin 14, type I | -2.67765 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -2.64849 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial | -2.63359 |
| LGALSL | lectin, galactoside-binding-like | -2.6059 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | -2.60052 |
| ACTR10 | actin-related protein 10 homolog (S. cerevisiae) | -2.5005 |
| DUSP14 | dual specificity phosphatase 14 | -2.32377 |
| RNF208 | ring finger protein 208 | -2.30762 |
| MLANA | melan-A | -2.30131 |
| NSG1 | neuron specific gene family member 1 | -2.29492 |
| PAEP | progestagen-associated endometrial protein | -2.25445 |
| MSMO1 | methylsterol monooxygenase 1 | -2.25123 |
| RFTN1 | raftlin, lipid raft linker 1 | -2.24986 |
| CLCNKA | chloride channel, voltage-sensitive Ka | -2.2339 |
| TRAF1 | TNF receptor-associated factor 1 | -2.20234 |
| KIFAP3 | kinesin-associated protein 3 | -2.19913 |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 | -2.12421 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | -2.10809 |
| TYR | tyrosinase | -2.07329 |
| PLS3 | plastin 3 | -2.06017 |
| SINHCAF | SIN3-HDAC complex associated factor | -2.05343 |
| SMYD2 | SET and MYND domain containing 2 | -2.0473 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | -2.03567 |
| DCT | dopachrome tautomerase | -2.02359 |
| MATN2 | matrilin 2 | -2.01401 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 | -2.01341 |
| NCF4 | neutrophil cytosolic factor 4, 40kDa | -2.01118 |
| OPTN | optineurin | -2.00166 |
