| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | theophylline 33.99 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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83 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:G02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | 5.28024 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 5.02471 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 3.42497 |
| UGDH | UDP-glucose 6-dehydrogenase | 3.42361 |
| TLR4 | toll-like receptor 4 | 2.57622 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 2.52694 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.47445 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 2.45934 |
| FBXO11 | F-box protein 11 | 2.40584 |
| NPIPB6 | nuclear pore complex interacting protein family, member B6 | 2.36828 |
| MTMR14 | myotubularin related protein 14 | 2.32768 |
| RMC1 | regulator of MON1-CCZ1 | 2.31916 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 | 2.29985 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | 2.26304 |
| MAGEB2 | melanoma antigen family B2 | 2.25189 |
| ZNF8 | zinc finger protein 8 | 2.23096 |
| APOE | apolipoprotein E | 2.22157 |
| CDC40 | cell division cycle 40 | 2.19748 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 2.19562 |
| TNFAIP8L2-SCNM1 | TNFAIP8L2-SCNM1 readthrough | 2.19329 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 | 2.18118 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | 2.17992 |
| CCDC28A | coiled-coil domain containing 28A | 2.17795 |
| TASP1 | taspase, threonine aspartase, 1 | 2.17758 |
| FIG4 | FIG4 phosphoinositide 5-phosphatase | 2.16905 |
| TMEM53 | transmembrane protein 53 | 2.15802 |
| MNS1 | meiosis-specific nuclear structural 1 | 2.15333 |
| ORM2 | orosomucoid 2 | 2.13098 |
| MAGEA2B | melanoma antigen family A2B | 2.13056 |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase | 2.12824 |
| C8A | complement component 8, alpha polypeptide | 2.12406 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 2.12195 |
| THAP10 | THAP domain containing 10 | 2.08922 |
| DENND2D | DENN/MADD domain containing 2D | 2.079 |
| GC | group-specific component (vitamin D binding protein) | 2.06825 |
| UBE2Q1 | ubiquitin-conjugating enzyme E2Q family member 1 | 2.06034 |
| TRAPPC11 | trafficking protein particle complex 11 | 2.03358 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 2.03308 |
| ZNF208 | zinc finger protein 208 | 2.0321 |
| BAG4 | BCL2-associated athanogene 4 | 2.02423 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 2.02371 |
| RAB36 | RAB36, member RAS oncogene family | 2.01667 |
| FEM1C | fem-1 homolog c (C. elegans) | 2.00934 |
| CENPI | centromere protein I | 2.00648 |
| YEATS2 | YEATS domain containing 2 | 2.0032 |
| Symbol | Name | Standardized Value |
|---|---|---|
| BASP1 | brain abundant, membrane attached signal protein 1 | -8.4705 |
| MRPS16 | mitochondrial ribosomal protein S16 | -5.4623 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -5.36754 |
| HAT1 | histone acetyltransferase 1 | -5.28749 |
| RNF167 | ring finger protein 167 | -5.14137 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.97975 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.10915 |
| TUBB6 | tubulin, beta 6 class V | -3.83358 |
| RXYLT1 | ribitol xylosyltransferase 1 | -3.48476 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | -2.81016 |
| ANXA2 | annexin A2 | -2.71026 |
| IFRD2 | interferon-related developmental regulator 2 | -2.68606 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.67335 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -2.58983 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 | -2.47204 |
| TMEM115 | transmembrane protein 115 | -2.46168 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 | -2.43198 |
| ORMDL2 | ORMDL sphingolipid biosynthesis regulator 2 | -2.38746 |
| CLDN15 | claudin 15 | -2.38645 |
| MRPS7 | mitochondrial ribosomal protein S7 | -2.30885 |
| SNX17 | sorting nexin 17 | -2.29179 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -2.28631 |
| PPP3CB | protein phosphatase 3, catalytic subunit, beta isozyme | -2.2819 |
| PSENEN | presenilin enhancer gamma secretase subunit | -2.26337 |
| LGALSL | lectin, galactoside-binding-like | -2.24007 |
| TEX264 | testis expressed 264 | -2.23648 |
| EPHB4 | EPH receptor B4 | -2.20517 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -2.20115 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -2.19075 |
| PSMD6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | -2.18922 |
| CCNB1 | cyclin B1 | -2.16493 |
| CLTB | clathrin, light chain B | -2.13736 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -2.04806 |
| EGLN2 | egl-9 family hypoxia-inducible factor 2 | -2.04694 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 | -2.04261 |
| SH2D1A | SH2 domain containing 1A | -2.02569 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 | -2.01574 |
| HTRA2 | HtrA serine peptidase 2 | -2.0018 |
