CRCGN016_MCF10A.WT.HP_24H:G03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description theophylline 11.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:G03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 4.56877
EPHB2 EPH receptor B2 3.84364
SSBP2 single-stranded DNA binding protein 2 3.76551
KLHL9 kelch-like family member 9 3.48578
DENND2D DENN/MADD domain containing 2D 2.90397
CERK ceramide kinase 2.68737
CAPN1 calpain 1, (mu/I) large subunit 2.43697
CHN1 chimerin 1 2.33671
ATMIN ATM interactor 2.19963
PRR15L proline rich 15-like 2.16377
ACAA1 acetyl-CoA acyltransferase 1 2.03822

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -5.09619
TM9SF3 transmembrane 9 superfamily member 3 -4.32492
KRT14 keratin 14, type I -4.31199
VAT1 vesicle amine transport 1 -4.24695
CHMP4B charged multivesicular body protein 4B -3.82467
MELK maternal embryonic leucine zipper kinase -3.29991
PSIP1 PC4 and SFRS1 interacting protein 1 -2.92395
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.53227
KDM3A lysine (K)-specific demethylase 3A -2.38739
TIMP1 TIMP metallopeptidase inhibitor 1 -2.36165
DUSP6 dual specificity phosphatase 6 -2.29724
SCAND1 SCAN domain containing 1 -2.05521