CRCGN016_MCF10A.WT.HP_24H:G04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description alpha-methyldopa sesquihydrate 100.97 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

21 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:G04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KCTD5 potassium channel tetramerization domain containing 5 3.58637
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 3.54054
CXCR4 chemokine (C-X-C motif) receptor 4 3.09649
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.73553
PDLIM1 PDZ and LIM domain 1 2.6668
PRKCQ protein kinase C, theta 2.59393
WDR7 WD repeat domain 7 2.40997
VAV3 vav 3 guanine nucleotide exchange factor 2.21262
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.07787

decreased expression

Symbol Name Standardized Value
BASP1 brain abundant, membrane attached signal protein 1 -4.19083
SLC25A46 solute carrier family 25, member 46 -4.1447
GDF15 growth differentiation factor 15 -4.0085
COG2 component of oligomeric golgi complex 2 -3.40393
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.28547
ADI1 acireductone dioxygenase 1 -3.23337
YME1L1 YME1-like 1 ATPase -3.19036
DIPK1A divergent protein kinase domain 1A -3.17718
CD58 CD58 molecule -2.72492
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) -2.40227
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.3076
XPO7 exportin 7 -2.24697