CRCGN016_MCF10A.WT.HP_24H:G05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description alpha-methyldopa sesquihydrate 33.66 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:G05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ACAA1 acetyl-CoA acyltransferase 1 3.95602
MCOLN1 mucolipin 1 3.80352
SNAP25 synaptosomal-associated protein, 25kDa 3.47494
COMP cartilage oligomeric matrix protein 3.30654
EPN2 epsin 2 2.38276
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.25597
CEP57 centrosomal protein 57kDa 2.19989

decreased expression

Symbol Name Standardized Value
HAT1 histone acetyltransferase 1 -3.66248
TNIP1 TNFAIP3 interacting protein 1 -3.15098
LDHD lactate dehydrogenase D -3.07648
TLCD3A TLC domain containing 3A -2.9179
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.62504
HEATR1 HEAT repeat containing 1 -2.58137
ARID4B AT rich interactive domain 4B (RBP1-like) -2.31103
TLK2 tousled-like kinase 2 -2.23968
BCAP29 B-cell receptor-associated protein 29 -2.05958
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.03296