CRCGN016_MCF10A.WT.HP_24H:G19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2-amino-5-nitrothiazole 96.3 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

50 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:G19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SNAP25 synaptosomal-associated protein, 25kDa 4.60323
HBA1 hemoglobin, alpha 1 3.72135
TBX2 T-box 2 3.36692
TESK1 testis-specific kinase 1 3.24443
EML3 echinoderm microtubule associated protein like 3 2.91089
HMOX1 heme oxygenase 1 2.67676
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 2.54333
OCRL oculocerebrorenal syndrome of Lowe 2.35903
STOML2 stomatin (EPB72)-like 2 2.33144
STMN2 stathmin 2 2.30501
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 2.29035
HBB hemoglobin, beta 2.28641
WDR5B WD repeat domain 5B 2.19065
CXCL2 chemokine (C-X-C motif) ligand 2 2.16783
ACTL6B actin-like 6B 2.15176
TBC1D12 TBC1 domain family, member 12 2.1496
VSNL1 visinin-like 1 2.10628
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.07991
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) 2.07764
HADH hydroxyacyl-CoA dehydrogenase 2.06293
PMFBP1 polyamine modulated factor 1 binding protein 1 2.05247
SAR1B secretion associated, Ras related GTPase 1B 2.03889
NQO1 NAD(P)H dehydrogenase, quinone 1 2.02889
TXNL4B thioredoxin-like 4B 2.02386
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 2.00596
CADM1 cell adhesion molecule 1 2.00146

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -5.44869
KIF14 kinesin family member 14 -5.14433
RNF167 ring finger protein 167 -3.94167
CCDC86 coiled-coil domain containing 86 -3.44866
MSN moesin -3.44176
PCCB propionyl CoA carboxylase, beta polypeptide -3.40779
TSPAN4 tetraspanin 4 -3.22271
ENOPH1 enolase-phosphatase 1 -3.05773
CD81 CD81 molecule -2.95931
RBM34 RNA binding motif protein 34 -2.53749
ACAA1 acetyl-CoA acyltransferase 1 -2.39887
RPIA ribose 5-phosphate isomerase A -2.39142
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.39079
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.30268
JMJD6 jumonji domain containing 6 -2.2847
TNIP1 TNFAIP3 interacting protein 1 -2.24981
S100A8 S100 calcium binding protein A8 -2.16006
ERP29 endoplasmic reticulum protein 29 -2.15901
FSTL1 follistatin-like 1 -2.13791
USP11 ubiquitin specific peptidase 11 -2.13207
HMG20B high mobility group 20B -2.07328
NUDC nudC nuclear distribution protein -2.05059
CRTAP cartilage associated protein -2.00955
PUF60 poly-U binding splicing factor 60KDa -2.0074