CRCGN016_MCF10A.WT.HP_24H:G22 Gene Set
Genes
45 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:G22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
WFS1
|
Wolfram syndrome 1 (wolframin)
|
4.83356
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
4.65925
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
4.49645
|
|
PDLIM1
|
PDZ and LIM domain 1
|
3.87729
|
|
DHRS2
|
dehydrogenase/reductase (SDR family) member 2
|
3.74624
|
|
NRBF2
|
nuclear receptor binding factor 2
|
2.72694
|
|
PDIA5
|
protein disulfide isomerase family A, member 5
|
2.7122
|
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
2.69775
|
|
AGR2
|
anterior gradient 2
|
2.6715
|
|
CCNF
|
cyclin F
|
2.65403
|
|
EFCC1
|
EF-hand and coiled-coil domain containing 1
|
2.38926
|
|
KLHDC8A
|
kelch domain containing 8A
|
2.36724
|
|
E2F6
|
E2F transcription factor 6
|
2.32229
|
|
COMP
|
cartilage oligomeric matrix protein
|
2.2291
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
2.16478
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
2.15095
|
|
SLC29A3
|
solute carrier family 29 (equilibrative nucleoside transporter), member 3
|
2.15003
|
|
DCHS2
|
dachsous cadherin-related 2
|
2.08781
|
|
FAM124B
|
family with sequence similarity 124B
|
2.07835
|
|
USP5
|
ubiquitin specific peptidase 5 (isopeptidase T)
|
2.07405
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.0639
|
|
SOCS4
|
suppressor of cytokine signaling 4
|
2.04662
|
|
ZNF197
|
zinc finger protein 197
|
2.02961
|
|
GLRA2
|
glycine receptor, alpha 2
|
2.02916
|
|
ZBED5
|
zinc finger, BED-type containing 5
|
2.01607
|
|
PIEZO1
|
piezo-type mechanosensitive ion channel component 1
|
2.00037
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
BASP1
|
brain abundant, membrane attached signal protein 1
|
-6.95286
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-5.26881
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-4.6722
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
-4.65481
|
|
PIK3C2B
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
|
-3.96218
|
|
GDF15
|
growth differentiation factor 15
|
-3.73618
|
|
KRT14
|
keratin 14, type I
|
-3.53852
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
-3.32857
|
|
CD81
|
CD81 molecule
|
-3.1111
|
|
MT1X
|
metallothionein 1X
|
-3.05426
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.81845
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.67774
|
|
FAM50A
|
family with sequence similarity 50, member A
|
-2.50747
|
|
CANT1
|
calcium activated nucleotidase 1
|
-2.46655
|
|
PPIB
|
peptidylprolyl isomerase B (cyclophilin B)
|
-2.18982
|
|
REEP5
|
receptor accessory protein 5
|
-2.14581
|
|
ATP6AP1
|
ATPase, H+ transporting, lysosomal accessory protein 1
|
-2.1147
|
|
HMG20B
|
high mobility group 20B
|
-2.08708
|
|
IDH3G
|
isocitrate dehydrogenase 3 (NAD+) gamma
|
-2.06032
|
