CRCGN016_MCF10A.WT.HP_24H:H01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1-[2,2-dichloro-1-(4-ethylphenyl)ethyl]-4-ethylbenzene 102.48 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

26 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:H01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GARRE1 granule associated Rac and RHOG effector 1 3.37213
COMP cartilage oligomeric matrix protein 2.98046
VGLL4 vestigial-like family member 4 2.38366
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.33328
CNPY3 canopy FGF signaling regulator 3 2.30573
TPD52L2 tumor protein D52-like 2 2.2081
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.07795

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -4.1611
ALDOC aldolase C, fructose-bisphosphate -3.88525
HSPA8 heat shock 70kDa protein 8 -3.73051
BID BH3 interacting domain death agonist -3.18489
CCDC86 coiled-coil domain containing 86 -3.04347
RPIA ribose 5-phosphate isomerase A -2.92229
ECH1 enoyl CoA hydratase 1, peroxisomal -2.91177
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.83864
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 -2.79508
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.31491
GDF15 growth differentiation factor 15 -2.28556
FZD7 frizzled class receptor 7 -2.23374
CREG1 cellular repressor of E1A-stimulated genes 1 -2.17655
HOXA4 homeobox A4 -2.12111
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -2.10202
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.05803
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -2.05365
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -2.04744
ACLY ATP citrate lyase -2.00732