CRCGN016_MCF10A.WT.HP_24H:H02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1-[2,2-dichloro-1-(4-ethylphenyl)ethyl]-4-ethylbenzene 34.16 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

24 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:H02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 4.39882
ADO 2-aminoethanethiol (cysteamine) dioxygenase 4.03886
MAMLD1 mastermind-like domain containing 1 3.39564
COMP cartilage oligomeric matrix protein 2.94058
AGR2 anterior gradient 2 2.66205
EPHB2 EPH receptor B2 2.54393
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.4581
MTA2 metastasis associated 1 family, member 2 2.28882
CASP2 caspase 2, apoptosis-related cysteine peptidase 2.14748
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 2.09875
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.09774
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.03255

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -4.78826
INSIG1 insulin induced gene 1 -4.73904
YME1L1 YME1-like 1 ATPase -3.46643
COG2 component of oligomeric golgi complex 2 -3.24228
SNCA synuclein, alpha (non A4 component of amyloid precursor) -2.79118
BASP1 brain abundant, membrane attached signal protein 1 -2.63419
TUBB6 tubulin, beta 6 class V -2.59789
RNF167 ring finger protein 167 -2.32338
FBXO21 F-box protein 21 -2.21918
TCEA2 transcription elongation factor A (SII), 2 -2.09812
ACAA1 acetyl-CoA acyltransferase 1 -2.04476
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 -2.03337