CRCGN016_MCF10A.WT.HP_24H:H06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description p-nitroaniline 11.16 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

19 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:H06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ITFG1 integrin alpha FG-GAP repeat containing 1 4.27894
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.86967
E2F2 E2F transcription factor 2 3.67361
CXCR4 chemokine (C-X-C motif) receptor 4 3.31463
ACAA1 acetyl-CoA acyltransferase 1 3.19912
GFOD1 glucose-fructose oxidoreductase domain containing 1 3.09099
EVL Enah/Vasp-like 2.71576
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.61861
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.59706
OLFML2B olfactomedin-like 2B 2.5866
CGRRF1 cell growth regulator with ring finger domain 1 2.23489

decreased expression

Symbol Name Standardized Value
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.6697
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.6576
BID BH3 interacting domain death agonist -3.00808
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.95993
ARID4B AT rich interactive domain 4B (RBP1-like) -2.92503
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -2.63223
CANT1 calcium activated nucleotidase 1 -2.62418
NGRN neugrin, neurite outgrowth associated -2.22068