| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 3,3',5,5'-tetrabromobisphenol a 11.22 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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42 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:H09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADAM10 | ADAM metallopeptidase domain 10 | 7.21456 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 3.76334 |
| AGR2 | anterior gradient 2 | 3.75544 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.55874 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 3.50459 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 3.44258 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 2.94632 |
| KLHL9 | kelch-like family member 9 | 2.69002 |
| OLFML2B | olfactomedin-like 2B | 2.58703 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 2.53799 |
| STMN2 | stathmin 2 | 2.51451 |
| LIPC | lipase, hepatic | 2.37547 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 2.30488 |
| NMD3 | NMD3 ribosome export adaptor | 2.26424 |
| ETNPPL | ethanolamine-phosphate phospho-lyase | 2.2426 |
| HBA1 | hemoglobin, alpha 1 | 2.21473 |
| HOXA5 | homeobox A5 | 2.16504 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.081 |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) | 2.02427 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SGK1 | serum/glucocorticoid regulated kinase 1 | -4.39995 |
| BAD | BCL2-associated agonist of cell death | -3.67732 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | -3.57648 |
| FBXO21 | F-box protein 21 | -2.84117 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | -2.60653 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.59208 |
| RPIA | ribose 5-phosphate isomerase A | -2.54446 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -2.4318 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -2.35525 |
| TENT4A | terminal nucleotidyltransferase 4A | -2.34895 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | -2.26235 |
| CCDC181 | coiled-coil domain containing 181 | -2.23603 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 | -2.23564 |
| STX11 | syntaxin 11 | -2.1539 |
| MTCH1 | mitochondrial carrier 1 | -2.13364 |
| MEP1A | meprin A, alpha (PABA peptide hydrolase) | -2.12263 |
| RBM34 | RNA binding motif protein 34 | -2.10208 |
| LTBP4 | latent transforming growth factor beta binding protein 4 | -2.08906 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 | -2.07336 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 | -2.04334 |
| FZD10 | frizzled class receptor 10 | -2.03661 |
| OSBPL11 | oxysterol binding protein-like 11 | -2.03603 |
| ATP1B4 | ATPase, Na+/K+ transporting, beta 4 polypeptide | -2.02146 |
