CRCGN016_MCF10A.WT.HP_24H:H10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description diallyl phthalate 99.45 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:H10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
KLHL21 kelch-like family member 21 5.079
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 3.79545
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.53548
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 2.68545
TXNL4B thioredoxin-like 4B 2.36395
CENPE centromere protein E, 312kDa 2.31885
MMP1 matrix metallopeptidase 1 2.22215
BAMBI BMP and activin membrane-bound inhibitor 2.1993
KAT7 K(lysine) acetyltransferase 7 2.1751
PDLIM1 PDZ and LIM domain 1 2.1421
CRELD2 cysteine-rich with EGF-like domains 2 2.14045

decreased expression

Symbol Name Standardized Value
BAG3 BCL2-associated athanogene 3 -4.7468
BAD BCL2-associated agonist of cell death -4.16227
CIAPIN1 cytokine induced apoptosis inhibitor 1 -4.05153
PTK2 protein tyrosine kinase 2 -3.4601
ARID4B AT rich interactive domain 4B (RBP1-like) -3.2713
BASP1 brain abundant, membrane attached signal protein 1 -3.0433
ACAA1 acetyl-CoA acyltransferase 1 -2.63205
LOC114841035 uncharacterized LOC114841035 -2.05805
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12) -2.041