CRCGN016_MCF10A.WT.HP_24H:H11 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description diallyl phthalate 33.15 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

30 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:H11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SATB1 SATB homeobox 1 3.27375
COMP cartilage oligomeric matrix protein 3.06276
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.88646
NCK2 NCK adaptor protein 2 2.84349
KIF5C kinesin family member 5C 2.80137
SPAG4 sperm associated antigen 4 2.76728
STIMATE STIM activating enhancer 2.73309
SMIM40 small integral membrane protein 40 2.63381
KDM5D lysine (K)-specific demethylase 5D 2.60141
AXIN1 axin 1 2.57051
TLCD3A TLC domain containing 3A 2.48397
BACE2 beta-site APP-cleaving enzyme 2 2.06287

decreased expression

Symbol Name Standardized Value
CCNB1 cyclin B1 -4.03732
PLK1 polo-like kinase 1 -3.9332
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.77596
ANXA2 annexin A2 -3.62436
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -3.25355
RXYLT1 ribitol xylosyltransferase 1 -3.07634
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.0084
S100A8 S100 calcium binding protein A8 -2.65309
ERC2 ELKS/RAB6-interacting/CAST family member 2 -2.51022
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -2.47102
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.42159
MRPL30 mitochondrial ribosomal protein L30 -2.21497
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -2.15409
SGK1 serum/glucocorticoid regulated kinase 1 -2.12882
HTRA1 HtrA serine peptidase 1 -2.10215
EIF5 eukaryotic translation initiation factor 5 -2.07878
SPTB spectrin, beta, erythrocytic -2.07727
ZNF415 zinc finger protein 415 -2.05988