CRCGN016_MCF10A.WT.HP_24H:H13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description barium chloride dihydrate 101.98 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:H13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.98362
DENND2D DENN/MADD domain containing 2D 3.60863
SRC SRC proto-oncogene, non-receptor tyrosine kinase 3.40064
SPAG4 sperm associated antigen 4 3.32848
TSEN2 TSEN2 tRNA splicing endonuclease subunit 3.15271
NCK2 NCK adaptor protein 2 2.88292
BACE2 beta-site APP-cleaving enzyme 2 2.60192
GRB10 growth factor receptor-bound protein 10 2.46266
AGR2 anterior gradient 2 2.3197
PDLIM1 PDZ and LIM domain 1 2.17401
GFOD1 glucose-fructose oxidoreductase domain containing 1 2.17195
PDIA5 protein disulfide isomerase family A, member 5 2.01996

decreased expression

Symbol Name Standardized Value
HSPA8 heat shock 70kDa protein 8 -3.08397
TM9SF3 transmembrane 9 superfamily member 3 -3.01905
SCYL3 SCY1-like 3 (S. cerevisiae) -2.94856
ADI1 acireductone dioxygenase 1 -2.91499
YME1L1 YME1-like 1 ATPase -2.87543
LYPLA1 lysophospholipase I -2.7492
GADD45B growth arrest and DNA-damage-inducible, beta -2.696
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.66183
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.54491
RPIA ribose 5-phosphate isomerase A -2.52718
GDF15 growth differentiation factor 15 -2.34632
SCAND1 SCAN domain containing 1 -2.28341
PRCP prolylcarboxypeptidase (angiotensinase C) -2.21559
ARID4B AT rich interactive domain 4B (RBP1-like) -2.02964