CRCGN016_MCF10A.WT.HP_24H:H14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description barium chloride dihydrate 33.99 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

19 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:H14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 4.74086
AGR2 anterior gradient 2 4.04195
BACE2 beta-site APP-cleaving enzyme 2 3.04543
PRSS23 protease, serine, 23 2.86193
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 2.22388
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.16176
NDUFS1 NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) 2.08913
OLFML2B olfactomedin-like 2B 2.08404
MED17 mediator complex subunit 17 2.06624
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 2.00233

decreased expression

Symbol Name Standardized Value
CCNB1 cyclin B1 -4.52316
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.95885
RBM34 RNA binding motif protein 34 -3.53745
SGK1 serum/glucocorticoid regulated kinase 1 -2.55632
RPA3 replication protein A3, 14kDa -2.54567
FPGS folylpolyglutamate synthase -2.18062
GZMM granzyme M (lymphocyte met-ase 1) -2.12403
GGPS1 geranylgeranyl diphosphate synthase 1 -2.0486
KRT14 keratin 14, type I -2.01545