CRCGN016_MCF10A.WT.HP_24H:H21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description estriol 11.33 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

26 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:H21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADGRE5 adhesion G protein-coupled receptor E5 3.80927
C2CD2 C2 calcium-dependent domain containing 2 3.18569
EPHB2 EPH receptor B2 2.46868
PRMT3 protein arginine methyltransferase 3 2.43533
HAPSTR1 HUWE1 associated protein modifying stress responses 2.3944
TXNL4B thioredoxin-like 4B 2.38974
MCUR1 mitochondrial calcium uniporter regulator 1 2.3694
RIC8A RIC8 guanine nucleotide exchange factor A 2.32108
TCEAL4 transcription elongation factor A (SII)-like 4 2.21062
BZW2 basic leucine zipper and W2 domains 2 2.1957
SIRT3 sirtuin 3 2.13777
ADGRE2 adhesion G protein-coupled receptor E2 2.11486
ZBTB35 zinc finger and BTB domain containing 35 2.01995

decreased expression

Symbol Name Standardized Value
KRT14 keratin 14, type I -4.71952
HAT1 histone acetyltransferase 1 -3.41379
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.19344
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -3.14815
RALGDS ral guanine nucleotide dissociation stimulator -3.06811
CIAPIN1 cytokine induced apoptosis inhibitor 1 -3.02053
CHMP4B charged multivesicular body protein 4B -2.98511
THAP11 THAP domain containing 11 -2.79953
CLTB clathrin, light chain B -2.74219
SORBS3 sorbin and SH3 domain containing 3 -2.43461
S100A8 S100 calcium binding protein A8 -2.39773
NSDHL NAD(P) dependent steroid dehydrogenase-like -2.26722
CBR3 carbonyl reductase 3 -2.2126