CRCGN016_MCF10A.WT.HP_24H:H22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,2-bis(bromomethyl)-1,3-pro?panediol, technical grade 102.05 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

17 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:H22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAMLD1 mastermind-like domain containing 1 4.06414
AGR2 anterior gradient 2 3.66066
TBX2 T-box 2 3.49344
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 3.34984
COMP cartilage oligomeric matrix protein 3.13912
CXCR4 chemokine (C-X-C motif) receptor 4 2.99091
ABHD4 abhydrolase domain containing 4 2.8151
FGFR4 fibroblast growth factor receptor 4 2.80103
GPER1 G protein-coupled estrogen receptor 1 2.68105
TPD52L2 tumor protein D52-like 2 2.17173

decreased expression

Symbol Name Standardized Value
PCCB propionyl CoA carboxylase, beta polypeptide -5.49863
PUF60 poly-U binding splicing factor 60KDa -3.75269
ZDHHC6 zinc finger, DHHC-type containing 6 -3.64846
NT5DC2 5'-nucleotidase domain containing 2 -2.86809
GSDMD gasdermin D -2.47325
MSN moesin -2.39512
GDF15 growth differentiation factor 15 -2.222