CRCGN016_MCF10A.WT.HP_24H:H24 Gene Set
Genes
49 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:H24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
4.85406
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
4.51232
|
|
IDE
|
insulin-degrading enzyme
|
4.19199
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
3.67566
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
3.63075
|
|
PKN1
|
protein kinase N1
|
2.97783
|
|
COMP
|
cartilage oligomeric matrix protein
|
2.80236
|
|
GRB10
|
growth factor receptor-bound protein 10
|
2.75025
|
|
ALG8
|
ALG8, alpha-1,3-glucosyltransferase
|
2.61523
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
2.56135
|
|
DMTF1
|
cyclin D binding myb-like transcription factor 1
|
2.45158
|
|
AAMDC
|
adipogenesis associated, Mth938 domain containing
|
2.36256
|
|
ABCB6
|
ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
|
2.34109
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.3172
|
|
RSF1
|
remodeling and spacing factor 1
|
2.27688
|
|
SLC35A1
|
solute carrier family 35 (CMP-sialic acid transporter), member A1
|
2.25585
|
|
SMCO4
|
single-pass membrane protein with coiled-coil domains 4
|
2.23247
|
|
ZXDC
|
ZXD family zinc finger C
|
2.18993
|
|
TRPM4
|
transient receptor potential cation channel, subfamily M, member 4
|
2.1592
|
|
EMSY
|
EMSY transcriptional repressor, BRCA2 interacting
|
2.1022
|
|
APOE
|
apolipoprotein E
|
2.08947
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
2.08074
|
|
PIR
|
pirin (iron-binding nuclear protein)
|
2.07943
|
|
BAX
|
BCL2-associated X protein
|
2.02178
|
|
STAMBP
|
STAM binding protein
|
2.00985
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
STUB1
|
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
|
-5.22605
|
|
LAP3
|
leucine aminopeptidase 3
|
-5.19356
|
|
KIF20A
|
kinesin family member 20A
|
-3.38755
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
-3.29399
|
|
BID
|
BH3 interacting domain death agonist
|
-3.10579
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
-2.96457
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.77263
|
|
CREB1
|
cAMP responsive element binding protein 1
|
-2.70755
|
|
RHOT2
|
ras homolog family member T2
|
-2.59278
|
|
TOMM34
|
translocase of outer mitochondrial membrane 34
|
-2.58354
|
|
RHOH
|
ras homolog family member H
|
-2.45129
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.35276
|
|
QTMAN
|
queuosine-tRNA mannosyltransferase
|
-2.26595
|
|
SKAP1
|
src kinase associated phosphoprotein 1
|
-2.24845
|
|
FPGS
|
folylpolyglutamate synthase
|
-2.23836
|
|
HLA-DRB3
|
major histocompatibility complex, class II, DR beta 3
|
-2.16913
|
|
MRPL30
|
mitochondrial ribosomal protein L30
|
-2.138
|
|
UBE2NL
|
ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
|
-2.08804
|
|
ANKZF1
|
ankyrin repeat and zinc finger domain containing 1
|
-2.0684
|
|
P2RX5
|
purinergic receptor P2X, ligand gated ion channel, 5
|
-2.0271
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.02359
|
|
ITGA2
|
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
|
-2.0221
|
|
CDC42SE1
|
CDC42 small effector 1
|
-2.00535
|
|
BTG1
|
B-cell translocation gene 1, anti-proliferative
|
-2.00334
|