CRCGN016_MCF10A.WT.HP_24H:H24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 2,2-bis(bromomethyl)-1,3-pro?panediol, technical grade 11.34 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

49 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:H24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 4.85406
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.51232
IDE insulin-degrading enzyme 4.19199
GARRE1 granule associated Rac and RHOG effector 1 3.67566
GFOD1 glucose-fructose oxidoreductase domain containing 1 3.63075
PKN1 protein kinase N1 2.97783
COMP cartilage oligomeric matrix protein 2.80236
GRB10 growth factor receptor-bound protein 10 2.75025
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.61523
LYN LYN proto-oncogene, Src family tyrosine kinase 2.56135
DMTF1 cyclin D binding myb-like transcription factor 1 2.45158
AAMDC adipogenesis associated, Mth938 domain containing 2.36256
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 2.34109
CCL2 chemokine (C-C motif) ligand 2 2.3172
RSF1 remodeling and spacing factor 1 2.27688
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1 2.25585
SMCO4 single-pass membrane protein with coiled-coil domains 4 2.23247
ZXDC ZXD family zinc finger C 2.18993
TRPM4 transient receptor potential cation channel, subfamily M, member 4 2.1592
EMSY EMSY transcriptional repressor, BRCA2 interacting 2.1022
APOE apolipoprotein E 2.08947
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 2.08074
PIR pirin (iron-binding nuclear protein) 2.07943
BAX BCL2-associated X protein 2.02178
STAMBP STAM binding protein 2.00985

decreased expression

Symbol Name Standardized Value
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -5.22605
LAP3 leucine aminopeptidase 3 -5.19356
KIF20A kinesin family member 20A -3.38755
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -3.29399
BID BH3 interacting domain death agonist -3.10579
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -2.96457
EIF5 eukaryotic translation initiation factor 5 -2.77263
CREB1 cAMP responsive element binding protein 1 -2.70755
RHOT2 ras homolog family member T2 -2.59278
TOMM34 translocase of outer mitochondrial membrane 34 -2.58354
RHOH ras homolog family member H -2.45129
VDAC1 voltage-dependent anion channel 1 -2.35276
QTMAN queuosine-tRNA mannosyltransferase -2.26595
SKAP1 src kinase associated phosphoprotein 1 -2.24845
FPGS folylpolyglutamate synthase -2.23836
HLA-DRB3 major histocompatibility complex, class II, DR beta 3 -2.16913
MRPL30 mitochondrial ribosomal protein L30 -2.138
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) -2.08804
ANKZF1 ankyrin repeat and zinc finger domain containing 1 -2.0684
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 -2.0271
ACAA1 acetyl-CoA acyltransferase 1 -2.02359
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -2.0221
CDC42SE1 CDC42 small effector 1 -2.00535
BTG1 B-cell translocation gene 1, anti-proliferative -2.00334