CRCGN016_MCF10A.WT.HP_24H:I02 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methoxychlor 33.66 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

39 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:I02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PRR7 proline rich 7 (synaptic) 4.20721
AGR2 anterior gradient 2 4.0229
VAV3 vav 3 guanine nucleotide exchange factor 3.65628
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 3.27688
SLC75A1 solute carrier family 75 member 1 3.13446
TIAM1 T-cell lymphoma invasion and metastasis 1 2.76847
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.63155
PLEKHJ1 pleckstrin homology domain containing, family J member 1 2.47595
TMED3 transmembrane emp24 protein transport domain containing 3 2.44237
H2BC12 H2B clustered histone 12 2.30976
HAT1 histone acetyltransferase 1 2.2704
GPATCH8 G patch domain containing 8 2.26798
HMG20A high mobility group 20A 2.22952
NCK2 NCK adaptor protein 2 2.13056
RSBN1 round spermatid basic protein 1 2.12795

decreased expression

Symbol Name Standardized Value
ZDHHC6 zinc finger, DHHC-type containing 6 -4.69257
YME1L1 YME1-like 1 ATPase -4.16579
MSMO1 methylsterol monooxygenase 1 -4.03995
TXNDC9 thioredoxin domain containing 9 -3.57332
DYNLT3 dynein, light chain, Tctex-type 3 -3.46264
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -3.33996
CYCS cytochrome c, somatic -3.27965
CORO1A coronin, actin binding protein, 1A -3.20731
DHRS7 dehydrogenase/reductase (SDR family) member 7 -2.96339
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -2.90781
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.81192
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -2.72196
ALDOC aldolase C, fructose-bisphosphate -2.64369
INSIG1 insulin induced gene 1 -2.43998
ECH1 enoyl CoA hydratase 1, peroxisomal -2.41547
IDI1 isopentenyl-diphosphate delta isomerase 1 -2.32247
GHITM growth hormone inducible transmembrane protein -2.27537
SH3D19 SH3 domain containing 19 -2.21109
PRPF18 pre-mRNA processing factor 18 -2.15906
ABI1 abl-interactor 1 -2.15703
TTPAL tocopherol (alpha) transfer protein-like -2.09435
SAR1B secretion associated, Ras related GTPase 1B -2.03867
GADD45B growth arrest and DNA-damage-inducible, beta -2.03074
ATG4A autophagy related 4A, cysteine peptidase -2.01319