CRCGN016_MCF10A.WT.HP_24H:I03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methoxychlor 11.22 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

15 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:I03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ACAA1 acetyl-CoA acyltransferase 1 3.48202
KIF5C kinesin family member 5C 2.55054
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 2.25582
RTN2 reticulon 2 2.12817
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 2.08025

decreased expression

Symbol Name Standardized Value
MSMO1 methylsterol monooxygenase 1 -4.38397
TXNDC9 thioredoxin domain containing 9 -3.87128
DIPK1A divergent protein kinase domain 1A -3.74767
COG2 component of oligomeric golgi complex 2 -3.5806
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -3.07233
PSIP1 PC4 and SFRS1 interacting protein 1 -2.87871
HACD3 3-hydroxyacyl-CoA dehydratase 3 -2.61724
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.25815
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -2.23358
FPGS folylpolyglutamate synthase -2.02388