CRCGN016_MCF10A.WT.HP_24H:I04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description c.i. acid orange 10 101.47 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:I04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGR2 anterior gradient 2 4.83564
SNAP25 synaptosomal-associated protein, 25kDa 4.66386
WFS1 Wolfram syndrome 1 (wolframin) 4.51636
WIF1 WNT inhibitory factor 1 3.79826
TBX2 T-box 2 3.67793
MAST2 microtubule associated serine/threonine kinase 2 3.19355
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 2.73392
NEFL neurofilament, light polypeptide 2.68606
COPS7A COP9 signalosome subunit 7A 2.60442
NEFM neurofilament, medium polypeptide 2.5988
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 2.48137
CXCL13 chemokine (C-X-C motif) ligand 13 2.36818
MMP1 matrix metallopeptidase 1 2.34527
SYT1 synaptotagmin I 2.20114
SV2B synaptic vesicle glycoprotein 2B 2.08484
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.07001
SATB1 SATB homeobox 1 2.0569
STMN2 stathmin 2 2.03101
CEP15 centrosomal protein 15 2.01707

decreased expression

Symbol Name Standardized Value
UFM1 ubiquitin-fold modifier 1 -5.34364
CLTB clathrin, light chain B -4.63886
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -4.52913
KRT14 keratin 14, type I -4.42314
S100A8 S100 calcium binding protein A8 -4.42183
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -3.24056
HTRA1 HtrA serine peptidase 1 -3.0932
PPP1R13L protein phosphatase 1, regulatory subunit 13 like -2.45037
UBE2A ubiquitin-conjugating enzyme E2A -2.17564
DMWD dystrophia myotonica, WD repeat containing -2.08347
RPS5 ribosomal protein S5 -2.08192
GPA33 glycoprotein A33 (transmembrane) -2.08125
AMHR2 anti-Mullerian hormone receptor, type II -2.03068
RNF44 ring finger protein 44 -2.01813
AQP6 aquaporin 6, kidney specific -2.01473