CRCGN016_MCF10A.WT.HP_24H:I05 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description c.i. acid orange 10 33.82 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

26 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:I05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 4.88547
HMOX1 heme oxygenase 1 4.85175
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 4.53813
TBX2 T-box 2 4.39945
PLSCR1 phospholipid scramblase 1 4.11059
ADRB2 adrenoceptor beta 2, surface 3.97992
EPHB2 EPH receptor B2 3.75111
AGR2 anterior gradient 2 3.42882
RB1 retinoblastoma 1 2.59005
HBA1 hemoglobin, alpha 1 2.45262
MMP1 matrix metallopeptidase 1 2.11381
VAV3 vav 3 guanine nucleotide exchange factor 2.03626
SESN1 sestrin 1 2.0234
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 2.01982

decreased expression

Symbol Name Standardized Value
ACOT9 acyl-CoA thioesterase 9 -5.44406
KIF14 kinesin family member 14 -3.94587
TIMP1 TIMP metallopeptidase inhibitor 1 -3.83163
BASP1 brain abundant, membrane attached signal protein 1 -3.80661
PSIP1 PC4 and SFRS1 interacting protein 1 -3.78209
RPA3 replication protein A3, 14kDa -3.38181
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.25166
EIF5 eukaryotic translation initiation factor 5 -2.86926
CANT1 calcium activated nucleotidase 1 -2.46071
ANXA2 annexin A2 -2.25093
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -2.16833
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.01307