CRCGN016_MCF10A.WT.HP_24H:I06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description c.i. acid orange 10 11.27 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

18 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:I06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABHD6 abhydrolase domain containing 6 3.4851
FZD7 frizzled class receptor 7 2.60265
PCM1 pericentriolar material 1 2.52086
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 2.48083
TLCD3A TLC domain containing 3A 2.44306
DNASE1L3 deoxyribonuclease I-like 3 2.1527
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 2.06413

decreased expression

Symbol Name Standardized Value
TES testin LIM domain protein -4.9718
KIF14 kinesin family member 14 -4.71407
BASP1 brain abundant, membrane attached signal protein 1 -4.44825
CAB39 calcium binding protein 39 -4.30076
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -4.04011
HTRA1 HtrA serine peptidase 1 -3.0206
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit -2.28108
MTERF3 mitochondrial transcription termination factor 3 -2.26783
BPHL biphenyl hydrolase-like (serine hydrolase) -2.23047
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -2.03499
SPEG SPEG complex locus -2.02524