| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sulfafurazole 100.97 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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171 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:I07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AGR2 | anterior gradient 2 | 6.321 |
| KDM5D | lysine (K)-specific demethylase 5D | 5.56515 |
| E2F2 | E2F transcription factor 2 | 5.43875 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 5.4135 |
| TLR4 | toll-like receptor 4 | 4.9613 |
| HBA1 | hemoglobin, alpha 1 | 4.53685 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 4.5178 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 4.4623 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | 3.9376 |
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 | 3.75855 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 3.73725 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 3.70918 |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 | 3.70435 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 3.55095 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 3.40725 |
| ZFY | zinc finger protein, Y-linked | 3.37385 |
| TXNRD3 | thioredoxin reductase 3 | 3.27758 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked | 3.06645 |
| FPR2 | formyl peptide receptor 2 | 3.06078 |
| RPGR | retinitis pigmentosa GTPase regulator | 2.99255 |
| AGO4 | argonaute RISC catalytic component 4 | 2.9345 |
| OLFML2B | olfactomedin-like 2B | 2.91545 |
| ACAA1 | acetyl-CoA acyltransferase 1 | 2.81305 |
| CD99 | CD99 molecule | 2.80272 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) | 2.7736 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 2.752 |
| UBAC1 | UBA domain containing 1 | 2.7069 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 2.70235 |
| TLR8 | toll-like receptor 8 | 2.62675 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 2.5994 |
| HDAC1 | histone deacetylase 1 | 2.58365 |
| ADGRE1 | adhesion G protein-coupled receptor E1 | 2.4901 |
| NLGN4Y | neuroligin 4, Y-linked | 2.444 |
| GTF2H5 | general transcription factor IIH, polypeptide 5 | 2.4348 |
| SRPX | sushi-repeat containing protein, X-linked | 2.43315 |
| MLF1 | myeloid leukemia factor 1 | 2.42955 |
| SPACA9 | sperm acrosome associated 9 | 2.39175 |
| GASK1B | golgi associated kinase 1B | 2.3873 |
| DNAAF2 | dynein, axonemal, assembly factor 2 | 2.3863 |
| MEGF9 | multiple EGF-like-domains 9 | 2.3718 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 2.369 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | 2.3668 |
| EFHD2 | EF-hand domain family, member D2 | 2.36145 |
| NIPSNAP2 | nipsnap homolog 2 | 2.3567 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 2.35315 |
| CCL23 | chemokine (C-C motif) ligand 23 | 2.3496 |
| MAB21L1 | mab-21-like 1 (C. elegans) | 2.3432 |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 | 2.3403 |
| HIPK3 | homeodomain interacting protein kinase 3 | 2.33335 |
| PMPCA | peptidase (mitochondrial processing) alpha | 2.3193 |
| RAI1 | retinoic acid induced 1 | 2.306 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 2.28565 |
| EN2 | engrailed homeobox 2 | 2.27635 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 | 2.27365 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 | 2.26817 |
| LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 | 2.26782 |
| P2RY13 | purinergic receptor P2Y, G-protein coupled, 13 | 2.2651 |
| PTPN20 | protein tyrosine phosphatase, non-receptor type 20 | 2.25905 |
| MACROD1 | MACRO domain containing 1 | 2.2483 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 | 2.23887 |
| ODF2 | outer dense fiber of sperm tails 2 | 2.23345 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 2.22235 |
| CFP | complement factor properdin | 2.2217 |
| CCNA1 | cyclin A1 | 2.21205 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 2.21082 |
| DMXL2 | Dmx-like 2 | 2.19712 |
| RALGDS | ral guanine nucleotide dissociation stimulator | 2.1869 |
| TMEM231 | transmembrane protein 231 | 2.15062 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 2.1303 |
| GCA | grancalcin, EF-hand calcium binding protein | 2.11075 |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 | 2.10224 |
| FPR1 | formyl peptide receptor 1 | 2.1 |
| RNF31 | ring finger protein 31 | 2.095 |
| FRAT2 | frequently rearranged in advanced T-cell lymphomas 2 | 2.0944 |
| AGTPBP1 | ATP/GTP binding protein 1 | 2.0843 |
| VIPAS39 | VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog | 2.0841 |
| TSPAN14 | tetraspanin 14 | 2.0811 |
| TRIM32 | tripartite motif containing 32 | 2.0604 |
| KDM1A | lysine (K)-specific demethylase 1A | 2.0538 |
| CEP192 | centrosomal protein 192kDa | 2.0512 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 2.04205 |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma | 2.0366 |
| NUP153 | nucleoporin 153kDa | 2.0255 |
| BBOF1 | basal body orientation factor 1 | 2.02165 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 2.01825 |
| CCNO | cyclin O | 2.0102 |
| DCPS | decapping enzyme, scavenger | 2.00105 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -5.7282 |
| RNF167 | ring finger protein 167 | -5.22925 |
| KDM5C | lysine (K)-specific demethylase 5C | -4.88765 |
| TXNDC9 | thioredoxin domain containing 9 | -4.62475 |
| RPA3 | replication protein A3, 14kDa | -4.6228 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) | -3.7543 |
| MGRN1 | mahogunin ring finger 1, E3 ubiquitin protein ligase | -3.5654 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -3.42742 |
| SMC1A | structural maintenance of chromosomes 1A | -3.07145 |
| GDF15 | growth differentiation factor 15 | -2.91905 |
| LOC124905557 | eukaryotic translation initiation factor 1A, X-chromosomal | -2.89964 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -2.77392 |
| RBM34 | RNA binding motif protein 34 | -2.7543 |
| ADSS2 | adenylosuccinate synthase 2 | -2.7294 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | -2.6954 |
| METTL18 | methyltransferase like 18 | -2.6087 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -2.58195 |
| APEX2 | APEX nuclease (apurinic/apyrimidinic endonuclease) 2 | -2.5191 |
| NUP88 | nucleoporin 88kDa | -2.51868 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | -2.49455 |
| TMEM45A | transmembrane protein 45A | -2.4805 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -2.4649 |
| NAA60 | N(alpha)-acetyltransferase 60, NatF catalytic subunit | -2.45535 |
| ECI1 | enoyl-CoA delta isomerase 1 | -2.4536 |
| TUBA4A | tubulin, alpha 4a | -2.41455 |
| UNC50 | unc-50 homolog (C. elegans) | -2.4011 |
| MFGE8 | milk fat globule-EGF factor 8 protein | -2.40085 |
| CA2 | carbonic anhydrase II | -2.3973 |
| PUDP | pseudouridine 5'-phosphatase | -2.39255 |
| MT1X | metallothionein 1X | -2.38765 |
| PACSIN1 | protein kinase C and casein kinase substrate in neurons 1 | -2.37715 |
| DNASE1L2 | deoxyribonuclease I-like 2 | -2.3731 |
| EIF3J | eukaryotic translation initiation factor 3, subunit J | -2.3573 |
| ZNF500 | zinc finger protein 500 | -2.35282 |
| BFAR | bifunctional apoptosis regulator | -2.3468 |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 | -2.3464 |
| PRX | periaxin | -2.32935 |
| GJB1 | gap junction protein, beta 1, 32kDa | -2.3125 |
| S100A8 | S100 calcium binding protein A8 | -2.3088 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) | -2.30638 |
| TMEM259 | transmembrane protein 259 | -2.2886 |
| FAIM | Fas apoptotic inhibitory molecule | -2.2885 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -2.2852 |
| GDPD2 | glycerophosphodiester phosphodiesterase domain containing 2 | -2.2764 |
| MSN | moesin | -2.2665 |
| MIS12 | MIS12 kinetochore complex component | -2.2654 |
| MRTFB | myocardin related transcription factor B | -2.26165 |
| LAX1 | lymphocyte transmembrane adaptor 1 | -2.21485 |
| LRRK1 | leucine-rich repeat kinase 1 | -2.2107 |
| C4A | complement component 4A (Rodgers blood group) | -2.2081 |
| MNT | MAX network transcriptional repressor | -2.20335 |
| EMC6 | ER membrane protein complex subunit 6 | -2.1911 |
| NDEL1 | nudE neurodevelopment protein 1-like 1 | -2.19065 |
| PPL | periplakin | -2.1861 |
| H2AC7 | H2A clustered histone 7 | -2.16285 |
| S100A1 | S100 calcium binding protein A1 | -2.14815 |
| HERC2 | HECT and RLD domain containing E3 ubiquitin protein ligase 2 | -2.1455 |
| LCMT2 | leucine carboxyl methyltransferase 2 | -2.14375 |
| H2AC6 | H2A clustered histone 6 | -2.1258 |
| SV2A | synaptic vesicle glycoprotein 2A | -2.12365 |
| SLC22A17 | solute carrier family 22, member 17 | -2.12315 |
| HAND1 | heart and neural crest derivatives expressed 1 | -2.1214 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | -2.10185 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase | -2.09335 |
| FAM13B | family with sequence similarity 13, member B | -2.0875 |
| LRRC8D | leucine rich repeat containing 8 family, member D | -2.08715 |
| GGPS1 | geranylgeranyl diphosphate synthase 1 | -2.08655 |
| ADAP2 | ArfGAP with dual PH domains 2 | -2.0847 |
| UBN1 | ubinuclein 1 | -2.08113 |
| LIMD2 | LIM domain containing 2 | -2.07505 |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) | -2.06905 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -2.06594 |
| MYBBP1A | MYB binding protein (P160) 1a | -2.05985 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -2.05655 |
| NHEJ1 | nonhomologous end-joining factor 1 | -2.0549 |
| MFAP1 | microfibrillar-associated protein 1 | -2.04495 |
| RTF1 | Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | -2.03993 |
| H2BC5 | H2B clustered histone 5 | -2.03557 |
| PSMA5 | proteasome (prosome, macropain) subunit, alpha type, 5 | -2.02515 |
| SLC38A2 | solute carrier family 38, member 2 | -2.01888 |
| RPAP1 | RNA polymerase II associated protein 1 | -2.0161 |
| KDM6A | lysine (K)-specific demethylase 6A | -2.01133 |
| ACTN4 | actinin, alpha 4 | -2.00535 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | -2.0018 |
