CRCGN016_MCF10A.WT.HP_24H:I08 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description sulfafurazole 33.66 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

39 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:I08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABHD4 abhydrolase domain containing 4 5.2397
MAMLD1 mastermind-like domain containing 1 4.77144
ADO 2-aminoethanethiol (cysteamine) dioxygenase 4.76293
EPHB2 EPH receptor B2 3.8447
NFIL3 nuclear factor, interleukin 3 regulated 3.16752
COMP cartilage oligomeric matrix protein 3.09951
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.82576
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 2.62069
NRBF2 nuclear receptor binding factor 2 2.5751
MTM1 myotubularin 1 2.56732
PLSCR3 phospholipid scramblase 3 2.43982
SPDL1 spindle apparatus coiled-coil protein 1 2.37799
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 2.36797
AGR2 anterior gradient 2 2.36477
SESN1 sestrin 1 2.36335
SATB1 SATB homeobox 1 2.28496
STXBP1 syntaxin binding protein 1 2.18713
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.17478
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 2.15592
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 2.00738
ANKFY1 ankyrin repeat and FYVE domain containing 1 2.00548

decreased expression

Symbol Name Standardized Value
MAPK13 mitogen-activated protein kinase 13 -4.924
ACOT9 acyl-CoA thioesterase 9 -4.79083
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -4.68042
GDF15 growth differentiation factor 15 -4.49965
ARPP19 cAMP-regulated phosphoprotein, 19kDa -3.88095
KRT14 keratin 14, type I -3.18499
RPA3 replication protein A3, 14kDa -3.02274
LOC127933115 uncharacterized LOC127933115 -2.73369
S100A8 S100 calcium binding protein A8 -2.7315
HPCA hippocalcin -2.69707
MUTYH mutY homolog -2.66035
TGFB1I1 transforming growth factor beta 1 induced transcript 1 -2.4372
AP3S1 adaptor-related protein complex 3, sigma 1 subunit -2.28447
CXCL14 chemokine (C-X-C motif) ligand 14 -2.24443
EREG epiregulin -2.04152
PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein -2.0164
CCNH cyclin H -2.01429
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 -2.00808