CRCGN016_MCF10A.WT.HP_24H:I09 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description sulfafurazole 11.22 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

16 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:I09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
VAV3 vav 3 guanine nucleotide exchange factor 4.51197
NGRN neugrin, neurite outgrowth associated 4.34498
ACLY ATP citrate lyase 3.46147
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 2.46308

decreased expression

Symbol Name Standardized Value
TUBB6 tubulin, beta 6 class V -5.15122
HSPA8 heat shock 70kDa protein 8 -5.00415
DHRS7 dehydrogenase/reductase (SDR family) member 7 -4.99869
GDF15 growth differentiation factor 15 -4.32741
BASP1 brain abundant, membrane attached signal protein 1 -3.61186
DNM1L dynamin 1-like -2.74092
DERA deoxyribose-phosphate aldolase (putative) -2.35422
RNF167 ring finger protein 167 -2.26633
CIAPIN1 cytokine induced apoptosis inhibitor 1 -2.23316
KRT14 keratin 14, type I -2.02918
ANXA2 annexin A2 -2.02439
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -2.00028