CRCGN016_MCF10A.WT.HP_24H:I10 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description p-chloroaniline 100.3 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

12 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:I10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCNA1 cyclin A1 3.92147
HBA1 hemoglobin, alpha 1 3.90159
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 3.25581
SIRT3 sirtuin 3 2.91381
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 2.45628

decreased expression

Symbol Name Standardized Value
PYGL phosphorylase, glycogen, liver -3.7274
TRAPPC3 trafficking protein particle complex 3 -3.68199
BASP1 brain abundant, membrane attached signal protein 1 -3.59178
PTK2 protein tyrosine kinase 2 -2.65576
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 -2.17843
CHPF2 chondroitin polymerizing factor 2 -2.17831
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 -2.17406