| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | p-chloroaniline 11.14 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome) |
| Similar Terms | |
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99 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:I12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PRKCQ | protein kinase C, theta | 5.46161 |
| EPHB2 | EPH receptor B2 | 5.11884 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 4.77451 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 4.24827 |
| RSF1 | remodeling and spacing factor 1 | 3.68636 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 3.20072 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | 3.18923 |
| CHAD | chondroadherin | 3.16657 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 3.11496 |
| PKN1 | protein kinase N1 | 3.10246 |
| UVRAG | UV radiation resistance associated | 3.08806 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 3.05207 |
| ALG8 | ALG8, alpha-1,3-glucosyltransferase | 2.899 |
| TMEM109 | transmembrane protein 109 | 2.88852 |
| PCBP1 | poly(rC) binding protein 1 | 2.77046 |
| MSRA | methionine sulfoxide reductase A | 2.72537 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 2.62428 |
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 | 2.56419 |
| RPAP1 | RNA polymerase II associated protein 1 | 2.53422 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 | 2.41637 |
| EMSY | EMSY transcriptional repressor, BRCA2 interacting | 2.41167 |
| HBA1 | hemoglobin, alpha 1 | 2.40109 |
| SLC30A9 | solute carrier family 30 (zinc transporter), member 9 | 2.3523 |
| THAP12 | THAP domain containing 12 | 2.28815 |
| PEX26 | peroxisomal biogenesis factor 26 | 2.28151 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 2.27055 |
| MARCHF1 | membrane associated ring-CH-type finger 1 | 2.25751 |
| PDIA5 | protein disulfide isomerase family A, member 5 | 2.24351 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 2.22906 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 | 2.17734 |
| SPAG5 | sperm associated antigen 5 | 2.15103 |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa | 2.14305 |
| CAPN5 | calpain 5 | 2.1407 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | 2.13904 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 | 2.13578 |
| E2F2 | E2F transcription factor 2 | 2.1354 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 2.09643 |
| POLD3 | polymerase (DNA-directed), delta 3, accessory subunit | 2.0783 |
| ACOT8 | acyl-CoA thioesterase 8 | 2.07551 |
| TRIM21 | tripartite motif containing 21 | 2.07217 |
| NAGA | N-acetylgalactosaminidase, alpha- | 2.06419 |
| MYG1 | MYG1 exonuclease | 2.05771 |
| NARS2 | asparaginyl-tRNA synthetase 2, mitochondrial (putative) | 2.05508 |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase | 2.03127 |
| ARMCX5 | armadillo repeat containing, X-linked 5 | 2.00958 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ISOC1 | isochorismatase domain containing 1 | -4.95444 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -4.79985 |
| ADI1 | acireductone dioxygenase 1 | -4.78089 |
| PCNA | proliferating cell nuclear antigen | -4.66275 |
| JMJD6 | jumonji domain containing 6 | -4.44029 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.99219 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -3.76834 |
| GDF15 | growth differentiation factor 15 | -3.66475 |
| S100A8 | S100 calcium binding protein A8 | -3.6063 |
| MCM3 | minichromosome maintenance complex component 3 | -3.39049 |
| LDHD | lactate dehydrogenase D | -2.93244 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial | -2.90543 |
| DNM1L | dynamin 1-like | -2.85165 |
| MXRA7 | matrix-remodelling associated 7 | -2.85096 |
| KRT14 | keratin 14, type I | -2.78563 |
| MTERF3 | mitochondrial transcription termination factor 3 | -2.75404 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -2.67206 |
| ANXA10 | annexin A10 | -2.54073 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.52767 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.52374 |
| ZNF394 | zinc finger protein 394 | -2.49835 |
| CYB5R2 | cytochrome b5 reductase 2 | -2.4951 |
| BUD31 | BUD31 homolog (S. cerevisiae) | -2.46743 |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 | -2.39983 |
| NXT1 | nuclear transport factor 2-like export factor 1 | -2.38427 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -2.3348 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 | -2.32774 |
| MCM6 | minichromosome maintenance complex component 6 | -2.2494 |
| HOXA5 | homeobox A5 | -2.21267 |
| WRAP73 | WD repeat containing, antisense to TP73 | -2.20344 |
| MAVS | mitochondrial antiviral signaling protein | -2.19515 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -2.19501 |
| WDR45B | WD repeat domain 45B | -2.19458 |
| MOSPD3 | motile sperm domain containing 3 | -2.19081 |
| NDP | Norrie disease (pseudoglioma) | -2.18662 |
| SEC23B | Sec23 homolog B (S. cerevisiae) | -2.15275 |
| IL19 | interleukin 19 | -2.14831 |
| TMEM40 | transmembrane protein 40 | -2.14794 |
| NOP2 | NOP2 nucleolar protein | -2.1447 |
| LY6D | lymphocyte antigen 6 complex, locus D | -2.13549 |
| PTS | 6-pyruvoyltetrahydropterin synthase | -2.12438 |
| SELENOT | selenoprotein T | -2.11068 |
| MRPL18 | mitochondrial ribosomal protein L18 | -2.11048 |
| IFRD1 | interferon-related developmental regulator 1 | -2.08844 |
| IDH3B | isocitrate dehydrogenase 3 (NAD+) beta | -2.08516 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -2.06531 |
| SNX5 | sorting nexin 5 | -2.05126 |
| PDCL3 | phosducin-like 3 | -2.04906 |
| CALML5 | calmodulin-like 5 | -2.0274 |
| HAMP | hepcidin antimicrobial peptide | -2.02676 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -2.02595 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | -2.02421 |
| CYBA | cytochrome b-245, alpha polypeptide | -2.01568 |
| CENPB | centromere protein B, 80kDa | -2.00867 |
