CRCGN016_MCF10A.WT.HP_24H:I13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description triphenyl phosphate 99.3 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

47 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:I13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SPAG4 sperm associated antigen 4 3.73646
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 3.23057
ACAA1 acetyl-CoA acyltransferase 1 3.14667
CLNS1A chloride channel, nucleotide-sensitive, 1A 3.12173
RSF1 remodeling and spacing factor 1 3.06874
KDM5D lysine (K)-specific demethylase 5D 2.42008
S100A4 S100 calcium binding protein A4 2.3619
THAP12 THAP domain containing 12 2.26769
AGR2 anterior gradient 2 2.24835
AAMDC adipogenesis associated, Mth938 domain containing 2.2442
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.21604
HBB hemoglobin, beta 2.20445
NUCB2 nucleobindin 2 2.18954
CHN1 chimerin 1 2.18747
CD302 CD302 molecule 2.09027
IPCEF1 interaction protein for cytohesin exchange factors 1 2.0709
OLFML2B olfactomedin-like 2B 2.02892
PAAF1 proteasomal ATPase-associated factor 1 2.01763
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 2.00502

decreased expression

Symbol Name Standardized Value
ZDHHC6 zinc finger, DHHC-type containing 6 -5.60893
RPIA ribose 5-phosphate isomerase A -4.8366
GDF15 growth differentiation factor 15 -3.913
KIF20A kinesin family member 20A -3.79345
DSG2 desmoglein 2 -3.71602
JMJD6 jumonji domain containing 6 -3.48673
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble -3.37945
VAT1 vesicle amine transport 1 -3.2859
VDAC1 voltage-dependent anion channel 1 -2.71451
LPAR2 lysophosphatidic acid receptor 2 -2.61965
HOXA5 homeobox A5 -2.59943
ABRAXAS2 abraxas 2, BRISC complex subunit -2.52164
TCTA T-cell leukemia translocation altered -2.48103
ACSL5 acyl-CoA synthetase long-chain family member 5 -2.44023
CREG1 cellular repressor of E1A-stimulated genes 1 -2.39632
RHOBTB2 Rho-related BTB domain containing 2 -2.24846
UROS uroporphyrinogen III synthase -2.23563
HAND1 heart and neural crest derivatives expressed 1 -2.15543
FPGS folylpolyglutamate synthase -2.10728
PDZD8 PDZ domain containing 8 -2.07683
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.06508
KXD1 KxDL motif containing 1 -2.05296
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 -2.04982
DHRS3 dehydrogenase/reductase (SDR family) member 3 -2.04811
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -2.02599
AKAP12 A kinase (PRKA) anchor protein 12 -2.01736
ARR3 arrestin 3, retinal (X-arrestin) -2.00188
MSL2 male-specific lethal 2 homolog (Drosophila) -2.00126