CRCGN016_MCF10A.WT.HP_24H:I14 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description triphenyl phosphate 33.1 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:I14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AGR2 anterior gradient 2 4.64205
CARMIL1 capping protein regulator and myosin 1 linker 1 3.81738
MSRA methionine sulfoxide reductase A 3.18758
DHRS2 dehydrogenase/reductase (SDR family) member 2 2.90201
S100A4 S100 calcium binding protein A4 2.70001
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.67387
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 2.66062
CXCR4 chemokine (C-X-C motif) receptor 4 2.35504
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 2.26243
ADRB2 adrenoceptor beta 2, surface 2.2371
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 2.02731

decreased expression

Symbol Name Standardized Value
GDF15 growth differentiation factor 15 -4.86423
ARID4B AT rich interactive domain 4B (RBP1-like) -4.29077
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.47367
FASTKD5 FAST kinase domains 5 -2.92595
PCCB propionyl CoA carboxylase, beta polypeptide -2.69611
TCEA2 transcription elongation factor A (SII), 2 -2.50804
ATG3 autophagy related 3 -2.39878
HOXA5 homeobox A5 -2.37988
TENT4A terminal nucleotidyltransferase 4A -2.29382
CREG1 cellular repressor of E1A-stimulated genes 1 -2.27375
GFI1B growth factor independent 1B transcription repressor -2.24868
SNCA synuclein, alpha (non A4 component of amyloid precursor) -2.19798
FBXO21 F-box protein 21 -2.19434
RXYLT1 ribitol xylosyltransferase 1 -2.15118