CRCGN016_MCF10A.WT.HP_24H:I15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description triphenyl phosphate 11.03 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

32 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:I15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADO 2-aminoethanethiol (cysteamine) dioxygenase 5.4211
HBA1 hemoglobin, alpha 1 4.93641
COMP cartilage oligomeric matrix protein 4.14258
ABHD6 abhydrolase domain containing 6 3.85998
E2F2 E2F transcription factor 2 3.5387
FAT1 FAT atypical cadherin 1 3.44883
GATA2 GATA binding protein 2 2.98109
SOAT2 sterol O-acyltransferase 2 2.82164
INTS3 integrator complex subunit 3 2.8133
OLFML2B olfactomedin-like 2B 2.61596
EXOSC4 exosome component 4 2.56811
SORD sorbitol dehydrogenase 2.47163
AGR2 anterior gradient 2 2.38032
EPHA3 EPH receptor A3 2.31181
ZNF510 zinc finger protein 510 2.22221
PEX12 peroxisomal biogenesis factor 12 2.19359
NRBF2 nuclear receptor binding factor 2 2.16141
HBB hemoglobin, beta 2.1152
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 2.09876
ZNF7 zinc finger protein 7 2.02347

decreased expression

Symbol Name Standardized Value
CRK v-crk avian sarcoma virus CT10 oncogene homolog -5.08387
OXA1L oxidase (cytochrome c) assembly 1-like -3.54578
DNM1L dynamin 1-like -3.46918
PFN1 profilin 1 -2.92007
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.70875
BASP1 brain abundant, membrane attached signal protein 1 -2.66571
ARID4B AT rich interactive domain 4B (RBP1-like) -2.3893
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial -2.37569
TENT4A terminal nucleotidyltransferase 4A -2.23127
FLCN folliculin -2.18988
SGK1 serum/glucocorticoid regulated kinase 1 -2.1875
STXBP2 syntaxin binding protein 2 -2.16857