CRCGN016_MCF10A.WT.HP_24H:I17 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ditiocarb-sodium-trihydrate 33.1 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

23 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:I17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DHRS2 dehydrogenase/reductase (SDR family) member 2 3.07682
GPC1 glypican 1 2.94159
SSBP2 single-stranded DNA binding protein 2 2.78283
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.58689
CCP110 centriolar coiled coil protein 110kDa 2.57629
MAMLD1 mastermind-like domain containing 1 2.53676
AGR2 anterior gradient 2 2.45547
USP6NL USP6 N-terminal like 2.35546
RSF1 remodeling and spacing factor 1 2.26233
PPARG peroxisome proliferator-activated receptor gamma 2.24194
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 2.20509
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.15312
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.12556
SATB1 SATB homeobox 1 2.08628
COMP cartilage oligomeric matrix protein 2.00042

decreased expression

Symbol Name Standardized Value
CD320 CD320 molecule -4.5323
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -4.48064
KIF20A kinesin family member 20A -2.5362
ACOT9 acyl-CoA thioesterase 9 -2.51203
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.48156
ARID4B AT rich interactive domain 4B (RBP1-like) -2.40542
TLCD3A TLC domain containing 3A -2.34673
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.25128