CRCGN016_MCF10A.WT.HP_24H:I18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ditiocarb-sodium-trihydrate 11.03 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

20 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:I18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADGRE5 adhesion G protein-coupled receptor E5 4.76969
PPARG peroxisome proliferator-activated receptor gamma 4.31306
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 4.24383
AGR2 anterior gradient 2 3.84587
DHRS2 dehydrogenase/reductase (SDR family) member 2 3.67139
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.87361
UGDH UDP-glucose 6-dehydrogenase 2.76086
CCNA1 cyclin A1 2.69147
GPATCH8 G patch domain containing 8 2.63547
AMDHD2 amidohydrolase domain containing 2 2.39479
IGHMBP2 immunoglobulin mu binding protein 2 2.20394
ACAA1 acetyl-CoA acyltransferase 1 2.19123
PXMP2 peroxisomal membrane protein 2, 22kDa 2.03174
RPP38 ribonuclease P/MRP 38kDa subunit 2.02115

decreased expression

Symbol Name Standardized Value
TXNDC9 thioredoxin domain containing 9 -4.79508
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -4.47783
CANT1 calcium activated nucleotidase 1 -3.3685
BASP1 brain abundant, membrane attached signal protein 1 -2.66484
GDF15 growth differentiation factor 15 -2.48762
NVL nuclear VCP-like -2.05219