CRCGN016_MCF10A.WT.HP_24H:I21 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 1,2-dichlorobenzene 11.2 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

39 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:I21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.73749
CDCA4 cell division cycle associated 4 2.70948
CLNS1A chloride channel, nucleotide-sensitive, 1A 2.69096
AAMDC adipogenesis associated, Mth938 domain containing 2.52928
ALG8 ALG8, alpha-1,3-glucosyltransferase 2.40625
COMP cartilage oligomeric matrix protein 2.35653
THAP12 THAP domain containing 12 2.33892
RSF1 remodeling and spacing factor 1 2.26795
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.19071
ERCC6L excision repair cross-complementation group 6-like 2.16862
TJP1 tight junction protein 1 2.12948
PKN1 protein kinase N1 2.08799
SESN1 sestrin 1 2.01503

decreased expression

Symbol Name Standardized Value
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide -5.76998
GDF15 growth differentiation factor 15 -4.00489
UFM1 ubiquitin-fold modifier 1 -3.88183
NUP85 nucleoporin 85kDa -3.86576
SLC35B1 solute carrier family 35, member B1 -3.81301
PUF60 poly-U binding splicing factor 60KDa -3.21666
SLC35F2 solute carrier family 35, member F2 -2.9699
NAT9 N-acetyltransferase 9 (GCN5-related, putative) -2.85582
PTK2 protein tyrosine kinase 2 -2.68697
HMG20B high mobility group 20B -2.67155
CHMP7 charged multivesicular body protein 7 -2.44707
SRSF4 serine/arginine-rich splicing factor 4 -2.44168
PFN1 profilin 1 -2.24889
TRIB3 tribbles pseudokinase 3 -2.23777
CRK v-crk avian sarcoma virus CT10 oncogene homolog -2.19962
OXA1L oxidase (cytochrome c) assembly 1-like -2.18543
MRPS7 mitochondrial ribosomal protein S7 -2.17274
TMEM94 transmembrane protein 94 -2.16823
GNAS GNAS complex locus -2.15945
SAP30BP SAP30 binding protein -2.14414
CALM2 calmodulin 2 (phosphorylase kinase, delta) -2.13452
LLGL2 lethal giant larvae homolog 2 (Drosophila) -2.11568
RXYLT1 ribitol xylosyltransferase 1 -2.10892
LOC100533997 MAGEA10-MAGEA5 readthrough -2.08273
ANXA2 annexin A2 -2.07054
MAGEA12 melanoma antigen family A12 -2.04157