CRCGN016_MCF10A.WT.HP_24H:I22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description succinic anhydride 101.47 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

30 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:I22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCR4 chemokine (C-X-C motif) receptor 4 4.34145
CHMP6 charged multivesicular body protein 6 4.04676
PPP1R13B protein phosphatase 1, regulatory subunit 13B 3.85409
TCEAL4 transcription elongation factor A (SII)-like 4 3.10412
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 2.82072
PRKCH protein kinase C, eta 2.73512
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 2.72933
RAB21 RAB21, member RAS oncogene family 2.63504
CADM1 cell adhesion molecule 1 2.48357
PECR peroxisomal trans-2-enoyl-CoA reductase 2.47888
MAP7 microtubule-associated protein 7 2.36369
AXIN1 axin 1 2.2737
SPAG4 sperm associated antigen 4 2.27204
VDAC3 voltage-dependent anion channel 3 2.17701

decreased expression

Symbol Name Standardized Value
BASP1 brain abundant, membrane attached signal protein 1 -8.00662
NUP85 nucleoporin 85kDa -4.39291
CANT1 calcium activated nucleotidase 1 -4.35232
HOXA5 homeobox A5 -4.2228
SLC35F2 solute carrier family 35, member F2 -4.00499
KIF20A kinesin family member 20A -3.85278
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -3.68769
KCTD2 potassium channel tetramerization domain containing 2 -3.03946
CBR3 carbonyl reductase 3 -2.99567
TIMP1 TIMP metallopeptidase inhibitor 1 -2.73161
TMEM94 transmembrane protein 94 -2.48614
TXLNA taxilin alpha -2.42805
MRPS7 mitochondrial ribosomal protein S7 -2.20878
GDF15 growth differentiation factor 15 -2.08376
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.07439
CDR2L cerebellar degeneration-related protein 2-like -2.07217