CRCGN016_MCF10A.WT.HP_24H:I23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description succinic anhydride 33.82 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

29 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:I23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ADO 2-aminoethanethiol (cysteamine) dioxygenase 5.00446
AGR2 anterior gradient 2 4.66125
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 3.57156
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 3.51416
TSPAN6 tetraspanin 6 2.92495
ABHD4 abhydrolase domain containing 4 2.30287
ALOX15 arachidonate 15-lipoxygenase 2.27231
NRBF2 nuclear receptor binding factor 2 2.26111
TBC1D12 TBC1 domain family, member 12 2.25668
DCHS2 dachsous cadherin-related 2 2.24876
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 2.15345
ATP9B ATPase, class II, type 9B 2.00316

decreased expression

Symbol Name Standardized Value
SLC35F2 solute carrier family 35, member F2 -5.08599
CBR3 carbonyl reductase 3 -3.62469
MTERF3 mitochondrial transcription termination factor 3 -3.57647
DERA deoxyribose-phosphate aldolase (putative) -3.54831
HEATR1 HEAT repeat containing 1 -3.17735
KIF14 kinesin family member 14 -3.16283
SNCA synuclein, alpha (non A4 component of amyloid precursor) -2.93581
MT1X metallothionein 1X -2.70587
BASP1 brain abundant, membrane attached signal protein 1 -2.44383
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -2.1672
CCNH cyclin H -2.15415
EVA1B eva-1 homolog B (C. elegans) -2.13909
TOMM34 translocase of outer mitochondrial membrane 34 -2.13551
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -2.05174
VAMP5 vesicle-associated membrane protein 5 -2.02295
SRFBP1 serum response factor binding protein 1 -2.00808
SRSF4 serine/arginine-rich splicing factor 4 -2.00061