CRCGN016_MCF10A.WT.HP_24H:I24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description succinic anhydride 11.27 um perturbation at 24 h in MCF10A.WT.HP (Carcinogenome)
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Genes

37 genes differentially expressed following the CRCGN016_MCF10A.WT.HP_24H:I24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
AXIN1 axin 1 5.17982
AGR2 anterior gradient 2 5.09133
COMP cartilage oligomeric matrix protein 5.02192
SNAP25 synaptosomal-associated protein, 25kDa 4.93736
SNAP91 synaptosomal-associated protein, 91kDa 3.32727
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 3.28377
IGHMBP2 immunoglobulin mu binding protein 2 3.11515
ABHD4 abhydrolase domain containing 4 3.09579
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 2.90262
GATA2 GATA binding protein 2 2.76083
NEFM neurofilament, medium polypeptide 2.62946
SPAG4 sperm associated antigen 4 2.62451
EPHB2 EPH receptor B2 2.56096
MAP7 microtubule-associated protein 7 2.50669
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.35903
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 2.29462
STMN2 stathmin 2 2.23536
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.22796
SH3BP1 SH3-domain binding protein 1 2.20709
SESN1 sestrin 1 2.20439
NEFL neurofilament, light polypeptide 2.16629
SCG3 secretogranin III 2.15351
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 2.11974
TTC38 tetratricopeptide repeat domain 38 2.05226
RGS7 regulator of G-protein signaling 7 2.03644
MEPE matrix extracellular phosphoglycoprotein 2.03041

decreased expression

Symbol Name Standardized Value
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 -5.32874
PCCB propionyl CoA carboxylase, beta polypeptide -4.95107
NSDHL NAD(P) dependent steroid dehydrogenase-like -4.27182
MT1X metallothionein 1X -3.05333
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.90362
PRPF4 pre-mRNA processing factor 4 -2.82379
EOLA1 endothelium and lymphocyte associated ASCH domain 1 -2.27865
S100A8 S100 calcium binding protein A8 -2.20851
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.16959
TGDS TDP-glucose 4,6-dehydratase -2.05534
CETN2 centrin, EF-hand protein, 2 -2.00978